Sorbonne University, Infectious Diseases Department, Pitié-Salpêtrière Hospital, AP-HP, Pierre-Louis Epidemiology and Public Health institute (iPLESP), Inserm 1136, Paris, France.
AP-HP, Infectious Diseases Department, Pitié-Salpêtrière Hospital, Paris, France.
Infect Dis Now. 2022 May;52(3):165-169. doi: 10.1016/j.idnow.2022.02.005. Epub 2022 Feb 11.
To describe persistent symptoms in long COVID-19 non-severe outpatients and report the 6-month clinical recovery (CR) rate.
Observational study enrolling outpatients (≥ 18 years) with confirmed non-severe COVID-19 (positive nasopharyngeal RT-PCR or presence of SARS-CoV-2 antibodies) who consulted for persistent symptoms after the first pandemic wave (March-May 2020). CR was assessed at the 6-month visit and defined as complete (no symptom), partial (persistent symptoms of lower intensity) or lack of recovery (no improvement).
Sixty-three patients (79% women, mean age: 48 years) enrolled; main symptoms (mean 81 days after acute infection): asthenia/myalgia (77%), dyspnea (51%), headaches (35%), cough (33%). At 6 months (n=56), 30% had complete, 57% partial, and 13% lack of recovery. The proportion of patients with>2 persistent symptoms was 26% at 6 months (main symptoms: dyspnea [54%] and asthenia/myalgia [46%]).
We observed a slow but high recovery rate at 6 months among these outpatients.
描述长新冠非重症门诊患者的持续症状，并报告 6 个月的临床康复（CR）率。
观察性研究纳入了在首次大流行期间（2020 年 3 月至 5 月）因持续症状而咨询的确诊非重症 COVID-19（鼻咽 RT-PCR 阳性或 SARS-CoV-2 抗体存在）的门诊患者（≥18 岁）。在 6 个月的就诊时评估 CR，并定义为完全（无症状）、部分（症状持续存在但强度降低）或无恢复（无改善）。
共纳入 63 例患者（79%为女性，平均年龄：48 岁）；主要症状（急性感染后 81 天平均出现）：乏力/肌痛（77%）、呼吸困难（51%）、头痛（35%）、咳嗽（33%）。在 6 个月时（n=56），30%完全康复，57%部分康复，13%无恢复。6 个月时有>2 种持续症状的患者比例为 26%（主要症状：呼吸困难[54%]和乏力/肌痛[46%]）。
我们观察到这些门诊患者在 6 个月时的康复率较慢但较高。
