College of Food Science and Engineering, Shandong Agricultural University, Taian 271018, China; Qilu University of Technology (Shandong Academy of Sciences), Shandong Analysis and Test Center, Key Laboratory for Applied Technology of Sophisticated Analytical Instruments of Shandong Province, Jinan 250014, China.
Quality Department, Sinotruk Jinan Truck Co., Ltd., Jinan 250000, China.
Food Chem. 2022 Jul 30;383:132396. doi: 10.1016/j.foodchem.2022.132396. Epub 2022 Feb 9.
Development of efficient and sensitive adsorbent for capturing phenoxy carboxylic acids (PCAs) from environmental and food samples is necessary because PCAs could threaten human health. Designing nanoparticle with multiple functional groups is beneficial to achieve the strong adsorption interaction and the specific recognition for target compound. In this paper, TpTG as an ionic covalent organic framework (ICOF), that could offer plenty of positive charges and hydrogen-bonding sites, was fabricated. TpTG achieved quicker, more sensitive enrichment for anionic PCAs. The analysis of binding affinity by density functional theory (DFT) demonstrated that PCAs bonded to TpTG primarily via electrostatic attraction, N H···O and O H···O, and C H···π interaction. The quantitative approach indicated low limits of detection (0.016-0.036 ng·g for rice and 0.43-0.78 ng·L for water). Furthermore, successfully determining PCAs emitted from real samples indicated the applicability of TpTG.
开发从环境和食品样品中捕获苯氧羧酸 (PCAs) 的高效、灵敏吸附剂是必要的，因为 PCAs 可能会威胁到人类健康。设计具有多种官能团的纳米粒子有利于实现对目标化合物的强吸附相互作用和特异性识别。本文制备了 TpTG 作为一种离子共价有机骨架 (ICOF)，它可以提供大量的正电荷和氢键位点。TpTG 实现了对阴离子 PCA 的更快、更灵敏的富集。通过密度泛函理论 (DFT) 分析结合亲和力表明，PCA 主要通过静电吸引、N-H···O 和 O-H···O 以及 C-H···π 相互作用与 TpTG 结合。定量方法表明，检测限低（大米为 0.016-0.036ng·g，水为 0.43-0.78ng·L）。此外，成功测定了来自实际样品的 PCA 表明 TpTG 的适用性。
