在青春期月经周期不规律的情况中，卵巢多卵泡状态、高黄体生成素和雄激素血浆水平以及无排卵现象很常见且紧密相关。

Ovarian multifollicularity, high LH and androgen plasma levels, and anovulation are frequent and strongly linked in adolescent irregular cycles.

作者信息

Venturoli S, Porcu E, Fabbri R, Paradisi R, Gammi L, Passarini M, Orsini L F, Flamigni C

出版信息

Acta Endocrinol (Copenh). 1986 Mar;111(3):368-72. doi: 10.1530/acta.0.1110368.

DOI:10.1530/acta.0.1110368

Abstract

Ninety-seven adolescents (0.5-6.0 years in gynaecological age) suffering from various kinds of menstrual irregularities were studied and compared with 20 adults by performing ovarian ultrasonography and plasma hormonal determinations. High percentages of multifollicularity (57.7%) and enlarged ovaries (46.3%) were found in the entire group of adolescents. Adolescents with multifollicular ovaries (more than 4 cystic areas) showed higher percentages of luteinizing hormone (LH: 32%), testosterone (T: 34%), and androstenedione (A: 43%) levels exceeding the upper normal adult range than subjects with homogeneous (less than 4 cystic areas) ovaries (LH: 12%, T: 10%, A: 19%, respectively). Ovulation can further discriminate the adolescents: in fact, adolescents with homogeneous ovaries and ovulatory cycles have a hormonal pattern almost identical to that of adults. On the contrary, subjects with multifollicular ovaries and anovulatory cycles show low values of follicle-stimulating hormone (FSH) and high values of LH, T and A, significantly different from those in ovulatory subjects with homogeneous ovaries (P less than 0.005) and from those in adults (P less than 0.005).

摘要

对97名患有各种月经不调的青少年（妇科年龄0.5 - 6.0岁）进行了研究，并通过卵巢超声检查和血浆激素测定与20名成年人进行了比较。在整个青少年组中发现多卵泡（57.7%）和卵巢增大（46.3%）的比例很高。与卵巢均匀（少于4个囊性区域）的受试者相比，多卵泡卵巢（超过4个囊性区域）的青少年中促黄体生成素（LH：32%）、睾酮（T：34%）和雄烯二酮（A：43%）水平超过正常成人上限的比例更高（LH分别为12%、T为10%、A为19%）。排卵情况可以进一步区分青少年：事实上，卵巢均匀且有排卵周期的青少年的激素模式与成年人几乎相同。相反，多卵泡卵巢且无排卵周期的受试者促卵泡生成素（FSH）值低，LH、T和A值高，与卵巢均匀的排卵受试者（P < 0.005）和成年人（P < 0.005）有显著差异。