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岩藻依聚糖对淀粉消化的调节作用:体外及机制研究

Fucoidan Regulates Starch Digestion: In Vitro and Mechanistic Study.

作者信息

Koh Hui Si Audrey, Chong Jin Er Leonard, Lu Jun, Zhou Weibiao

机构信息

Centre for Life Sciences (CeLS), NUS Graduate School for Integrative Science and Engineering, National University of Singapore, 28 Medical Drive, Singapore 117456, Singapore.

Department of Food Science & Technology, National University of Singapore, Science Drive 2, Singapore 117542, Singapore.

出版信息

Foods. 2022 Feb 1;11(3):427. doi: 10.3390/foods11030427.

DOI:10.3390/foods11030427
PMID:35159577
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8834454/
Abstract

Bread is a high glycemic index (GI) food with high amounts of readily digestible carbohydrates. Fucoidan refers to a group of sulfated polysaccharides isolated from brown seaweed that has been gaining traction for its many functional properties, including its ability to inhibit starch hydrolases. In this study, fucoidan was added into bread to lower the glycemic index of bread. Fucoidan fortification at 3.0% reduced the starch digestion rate of baked bread by 21.5% as compared to control baked bread. This translated to a 17.7% reduction in the predicted GI (pGI) with 3.0% of fucoidan. Fucoidan was retained in the bread after baking. Although the in vitro bioavailability of fucoidan was negligible, the in vitro bioaccessibility of fucoidan was high, at 77.1-79.8%. This suggested that although fucoidan may not be absorbed via passive diffusion, there is potential for the fucoidan to be absorbed via other modes of absorption. Thus, there is a potential for the use of fucoidan as a functional ingredient in bread to reduce the glycemic potential of bread.

摘要

面包是一种具有高血糖生成指数(GI)的食物,含有大量易于消化的碳水化合物。岩藻依聚糖是从褐藻中分离出的一组硫酸化多糖,因其多种功能特性,包括抑制淀粉水解酶的能力,而越来越受到关注。在本研究中,将岩藻依聚糖添加到面包中以降低面包的血糖生成指数。与对照烘焙面包相比,添加3.0%岩藻依聚糖使烘焙面包的淀粉消化率降低了21.5%。这意味着添加3.0%岩藻依聚糖可使预测血糖生成指数(pGI)降低17.7%。烘焙后岩藻依聚糖保留在面包中。尽管岩藻依聚糖的体外生物利用度可忽略不计,但其体外生物可及性较高,为77.1 - 79.8%。这表明,虽然岩藻依聚糖可能无法通过被动扩散被吸收,但它有可能通过其他吸收方式被吸收。因此,将岩藻依聚糖用作面包中的功能成分以降低面包的血糖生成潜力具有可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2809/8834454/b34d1805b030/foods-11-00427-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2809/8834454/ba3e788e2653/foods-11-00427-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2809/8834454/5bbbfc8d4830/foods-11-00427-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2809/8834454/3b9b8c3cd654/foods-11-00427-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2809/8834454/108995c540aa/foods-11-00427-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2809/8834454/b34d1805b030/foods-11-00427-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2809/8834454/ba3e788e2653/foods-11-00427-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2809/8834454/5bbbfc8d4830/foods-11-00427-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2809/8834454/3b9b8c3cd654/foods-11-00427-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2809/8834454/108995c540aa/foods-11-00427-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2809/8834454/b34d1805b030/foods-11-00427-g005.jpg

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本文引用的文献

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Front Pharmacol. 2020 Jun 5;11:831. doi: 10.3389/fphar.2020.00831. eCollection 2020.
2
Structure characterization and antioxidant activity of fucoidan isolated from Undaria pinnatifida grown in New Zealand.新西兰产裙带菜中褐藻糖胶的结构表征和抗氧化活性。
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