抑郁症酗酒者的地塞米松抑制试验检测

Dexamethasone suppression test testing of depressed alcoholics.

作者信息

Dackis C A, Stuckey R F, Gold M S, Pottash A L

出版信息

Alcohol Clin Exp Res. 1986 Jan-Feb;10(1):59-60. doi: 10.1111/j.1530-0277.1986.tb05615.x.

DOI:10.1111/j.1530-0277.1986.tb05615.x

Abstract

In order to determine the sensitivity of the dexamethasone suppression test (DST) for major depression in alcoholics, we administered this test to 27 alcoholics with major depression. Sixteen of 27 had abnormal DST results, yielding a 59% sensitivity for depression in alcoholics. When combined with previously reported specificity findings of 100%, the DST significantly (p less than 0.001) distinguished depressed from nondepressed alcoholics.

摘要

为了确定地塞米松抑制试验（DST）对酒精性患者中重度抑郁症的敏感性，我们对27名患有重度抑郁症的酒精性患者进行了该试验。27名患者中有16名DST结果异常，酒精性患者抑郁症的敏感性为59%。结合之前报道的100%的特异性结果，DST能显著（p<0.001）区分抑郁和非抑郁的酒精性患者。