Kuo Yuh-Ruey, Cheng Ting-An, Chou Po-Hsin, Liu Yuan-Fu, Chang Chao-Jui, Chuang Cheng-Feng, Su Pei-Fang, Lin Ruey-Mo, Lin Cheng-Li
Department of Orthopedic Surgery, National Cheng Kung University Hospital, Tainan City 704, Taiwan.
School of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
J Clin Med. 2022 Jan 28;11(3):708. doi: 10.3390/jcm11030708.
Vertebral compression fractures, resulting in significant pain and disability, commonly occur in elderly osteoporotic patients. However, the current literature lacks long-term follow-up information related to image parameters and bone formation following vertebroplasty.
To evaluate new bone formation after vertebroplasty and the long-term effect of vertebroplasty.
A total of 157 patients with new osteoporotic compression fractures who underwent vertebroplasty were retrospectively analyzed. The image parameters, including wedge angles, compression ratios, global alignment, and new bone formation, were recorded before and after vertebroplasty up to three years postoperatively.
The wedge angle improved and was maintained for 12 months. The compression ratios also improved but gradually deteriorated during the follow-up period. New bone formation was found in 40% of the patients at 36 months, and the multivariate analysis showed that this might have been related to the correction of the anterior compression ratio.
Vertebroplasty significantly restored the wedge angles and compression ratios up to one year postoperatively, and new bone formation was noted on plain radiographs, which increased over time. Last, the restoration of vertebral parameters may contribute to new bone formation.
椎体压缩骨折常见于老年骨质疏松患者，会导致严重疼痛和功能障碍。然而，目前的文献缺乏与椎体成形术后图像参数和骨形成相关的长期随访信息。
评估椎体成形术后的新骨形成及椎体成形术的长期效果。
回顾性分析157例行椎体成形术的新发骨质疏松性压缩骨折患者。记录椎体成形术前及术后长达三年的图像参数，包括楔角、压缩率、整体对线情况和新骨形成情况。
楔角改善并维持了12个月。压缩率也有所改善，但在随访期间逐渐恶化。36个月时，40%的患者出现新骨形成，多因素分析表明这可能与前侧压缩率的矫正有关。
椎体成形术在术后一年内显著恢复了楔角和压缩率，平片上可见新骨形成，且随时间增加。最后，椎体参数的恢复可能有助于新骨形成。
