Department of Pharmacognosy, Faculty of Pharmacy, Poznan University of Medical Sciences, 4 Święcickiego St., 60-780 Poznan, Poland.
Department of Bromatology, Faculty of Pharmacy, Poznan University of Medical Sciences, 42 Marcelińska St., 60-354 Poznan, Poland.
Molecules. 2022 Jan 26;27(3):815. doi: 10.3390/molecules27030815.
Nowadays, increasingly more attention is being paid to a holistic approach to health, in which diet contributes to disease prevention. There is growing interest in functional food that not only provides basic nutrition but has also been demonstrated to be an opportunity for the prevention of disorders. A promising functional food is soybean, which is the richest source of the isoflavone, genistein. Genistein may be useful in the prevention and treatment of such disorders as psoriasis, cataracts, cystic fibrosis, non-alcoholic fatty liver disease and type 2 diabetes. However, achievable concentrations of genistein in humans are low, and the use of soybean as a functional food is not devoid of concerns, which are related to genistein's potential side effects resulting from its estrogenic and goitrogenic effects.
如今，人们越来越关注整体健康方法，其中饮食有助于预防疾病。人们对功能性食品越来越感兴趣，这些食品不仅提供基本营养，而且还被证明是预防疾病的机会。一种很有前途的功能性食品是大豆，它是异黄酮、染料木黄酮的最丰富来源。染料木黄酮可能对预防和治疗银屑病、白内障、囊性纤维化、非酒精性脂肪肝和 2 型糖尿病等疾病有帮助。然而，人类可达到的染料木黄酮浓度较低，而将大豆作为功能性食品使用并非没有顾虑，这与染料木黄酮的雌激素和致甲状腺肿作用所带来的潜在副作用有关。
