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Female sex hormone, progesterone, ameliorates the severity of SARS-CoV-2-caused pneumonia in the Syrian hamster model.

作者信息

Yuan Lunzhi, Zhu Huachen, Wu Kun, Zhou Ming, Ma Jian, Chen Rirong, Tang Qiyi, Cheng Tong, Guan Yi, Xia Ningshao

机构信息

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Sciences, School of Public Health, Xiamen University, Xiamen, Fujian, China.

State Key Laboratory of Emerging Infectious Diseases, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, SAR, China.

出版信息

Signal Transduct Target Ther. 2022 Feb 14;7(1):47. doi: 10.1038/s41392-021-00860-5.

DOI:10.1038/s41392-021-00860-5
PMID:35165265
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8844354/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd2d/8844354/958456c1be7a/41392_2021_860_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd2d/8844354/958456c1be7a/41392_2021_860_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd2d/8844354/958456c1be7a/41392_2021_860_Fig1_HTML.jpg

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Chest. 2021 Jul;160(1):74-84. doi: 10.1016/j.chest.2021.02.024. Epub 2021 Feb 20.
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Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes.TNF-α 和 IFN-γ 的协同作用可引发 SARS-CoV-2 感染和细胞因子休克综合征中的炎症细胞死亡、组织损伤和死亡。
Cell. 2021 Jan 7;184(1):149-168.e17. doi: 10.1016/j.cell.2020.11.025. Epub 2020 Nov 19.
3
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iScience. 2025 Jan 22;28(3):111875. doi: 10.1016/j.isci.2025.111875. eCollection 2025 Mar 21.
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Characterization of a SARS-CoV-2 Omicron BA.5 direct-contact transmission model in hamsters.仓鼠中新型冠状病毒奥密克戎BA.5直接接触传播模型的特征分析
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