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肺硬化性肺细胞瘤:肺结节的重要鉴别诊断

Pulmonary Sclerosing Pneumocytoma: An Essential Differential Diagnosis for a Lung Nodule.

作者信息

Manickam Rajapriya, Mechineni Ashesha

机构信息

Pulmonary/Critical Care Medicine, St. Joseph's University Medical Center, Paterson, USA.

Internal Medicine, St. Joseph's University Medical Center, Chicago, USA.

出版信息

Cureus. 2022 Jan 10;14(1):e21081. doi: 10.7759/cureus.21081. eCollection 2022 Jan.

DOI:10.7759/cureus.21081
PMID:35165545
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8826945/
Abstract

Pulmonary sclerosing pneumocytoma, previously known as pulmonary sclerosing hemangioma, is a rare benign lung tumor with a low prevalence. We present this condition in a 26-year-old, young, non-smoking female with a slow-growing pulmonary nodule incidentally noted on imaging. Serial computed tomography(CT) scans revealed slow growth, and invasive testing was recommended. The patient underwent a left lateral thoracotomy and based on frozen section findings. A left lower lobectomy was performed. The final pathological diagnosis revealed sclerosing pneumocytoma. This is an atypical patient demographic considering the propensity of the disease for middle-aged Asian women. The case presentation and work-up highlight this critical differential diagnosis for incidental pulmonary nodules increasingly being noted due to widespread use of imaging for screening and routine care in the current medical climate. There are no specific imaging criteria to diagnose this condition. The final diagnosis is made only after surgical biopsy and histopathology. No additional treatment is needed following the diagnosis.

摘要

肺硬化性细胞瘤,以前称为肺硬化性血管瘤,是一种罕见的良性肺肿瘤,发病率较低。我们报告了一名26岁的年轻非吸烟女性,其在影像学检查中偶然发现肺部有一个生长缓慢的结节。系列计算机断层扫描(CT)显示生长缓慢,建议进行侵入性检查。患者接受了左外侧开胸手术,并根据冰冻切片结果进行了左下肺叶切除术。最终病理诊断为硬化性细胞瘤。考虑到该疾病在中年亚洲女性中的倾向,这是一个非典型的患者人群。该病例报告及检查过程突出了在当前医疗环境中,由于广泛使用影像学进行筛查和常规护理,偶然发现的肺结节的这一关键鉴别诊断。目前尚无诊断该病的特异性影像学标准。只有在手术活检和组织病理学检查后才能做出最终诊断。诊断后无需额外治疗。

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Intern Med. 2025 Mar 15;64(6):893-897. doi: 10.2169/internalmedicine.3956-24. Epub 2024 Aug 8.
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Navigating the diagnostic maze: the challenge of sclerosing pneumocytoma in frozen sections.在冰冻切片中探寻硬化性肺细胞瘤的诊断迷宫:挑战重重
Int J Clin Exp Pathol. 2024 Jun 15;17(6):182-188. doi: 10.62347/KLWT4935. eCollection 2024.

本文引用的文献

1
Preoperative Diagnosis in 46 Cases of Pulmonary Sclerosing Hemangioma.46例肺硬化性血管瘤的术前诊断
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