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糖尿病的定义。

Definition of diabetes mellitus.

作者信息

Stogdale L

出版信息

Cornell Vet. 1986 Apr;76(2):156-74.

PMID:3516569
Abstract

The nomenclature of human diabetes mellitus (DM) has been revised, and this classification has been accepted throughout the medical world and literature. The major categories of diabetes are: insulin-dependent DM, type I or IDDM; noninsulin-dependent DM, type II or NIDDM; secondary DM or type S; impaired glucose tolerance, IGT; gestational diabetes; and previous abnormality of glucose tolerance, PrevAGT. A review of the literature has shown that over half of the documented diabetic dogs, with a single medical diagnosis, appear to be type I, IDDM, with a substantial proportion being type S, and the remainder being type II, NIDDM. Obesity is frequently associated with IGT and NIDDM. Diabetic cats most commonly have pancreatic islet destruction associated with pancreatic amyloidosis; they are insulin deficient, IDDM. The commonest causes of secondary diabetes in dogs are pancreatic damage, hyperadrenocorticism and hypersomatotropism secondary to persistent progesterone influence. Progestogen therapy is the most frequently reported cause of secondary diabetes in cats. Diabetes in horses is type S, usually secondary to a functional pituitary tumor but occasionally following chronic pancreatitis. The blood glucose ranges for normal, IGT and diabetic animals, and the normal serum insulin values of various species is tabulated.

摘要

人类糖尿病(DM)的命名法已经修订,并且这种分类已在整个医学界和文献中被接受。糖尿病的主要类型有:胰岛素依赖型糖尿病,I型或IDDM;非胰岛素依赖型糖尿病,II型或NIDDM;继发性糖尿病或S型;糖耐量受损,IGT;妊娠期糖尿病;以及既往糖耐量异常,PrevAGT。文献综述表明,在有单一医学诊断记录的糖尿病犬中,超过一半似乎是I型,即IDDM,其中相当一部分是S型,其余为II型,即NIDDM。肥胖常与IGT和NIDDM相关。糖尿病猫最常见的是胰腺胰岛破坏伴胰腺淀粉样变性;它们胰岛素缺乏,属于IDDM。犬继发性糖尿病最常见的原因是胰腺损伤、肾上腺皮质功能亢进以及持续孕酮影响继发的生长激素过多症。孕激素治疗是猫继发性糖尿病最常报道的原因。马的糖尿病为S型,通常继发于功能性垂体肿瘤,但偶尔也继发于慢性胰腺炎。列出了正常、IGT和糖尿病动物的血糖范围以及各种物种的正常血清胰岛素值。

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Definition of diabetes mellitus.糖尿病的定义。
Cornell Vet. 1986 Apr;76(2):156-74.
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[Glucose tolerance and insulin response in dogs with spontaneous diabetes, obesity and following prolonged fasting].[自发性糖尿病、肥胖及长期禁食犬的葡萄糖耐量和胰岛素反应]
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Diabetes mellitus and pancreatitis--cause or effect?糖尿病与胰腺炎——因果关系?
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