Department of Veterinary Medicine and Surgery, University of Missouri, Columbia, Missouri, USA.
Department of Veterinary Clinical Medicine, University of Illinois, 1008 W Hazelwood Drive, Urbana, Illinois, 61802, USA.
J Vet Emerg Crit Care (San Antonio). 2022 Mar;32(2):173-180. doi: 10.1111/vec.13155. Epub 2022 Feb 15.
To compare the level of agreement of measurement of analytes (sodium, chloride, potassium, urea nitrogen [UN], creatinine, glucose) in a population of healthy adult cats between the point-of-care (POC) analyzer and laboratory analyzer. To establish reference intervals for the POC analyzer in healthy adult cats.
Prospective observational study.
University teaching hospital.
Fifty-five cats were screened. Seven cats were excluded due to aggression that prohibited phlebotomy, and 1 cat was excluded due to prolonged restraint; 47 cats were enrolled.
None.
In this patient population, reference intervals for the POC analyzer were calculated: sodium 145-157 mmol/L; chloride 116-124 mmol/L; potassium 3.4-5.5 mmol/L; UN 5.71-13.9 mmol/L (16-39 mg/dl); creatinine 74.3-189.2 mmol/L (0.84-2.14 mg/dl); and glucose 4-11.8 mmol/L (72-213 mg/dl). Comparison between the POC analyzer and laboratory analyzer using the Bland-Altman method was performed. The bias for each analyte is as follows: sodium 1.55 mmol/L; chloride 0.99 mmol/L; potassium 0.21 mmol/L; UN -0.25 mmol/L (-0.7 mg/dl); creatinine 9.73 mmol/L (0.11 mg/dl); and glucose 0.5 mmol/L (9.79 mg/dl).
Reference intervals for each analyte were similar to other chemistry analyzers. There was no significant difference between the POC and laboratory analyzers in analysis of UN, with a statistically significant difference observed with sodium, potassium, chloride, creatinine, and glucose. However, the values are likely not sufficiently different to alter initial clinical decisions regarding patient care.
比较健康成年猫群体中即时检测（POC）分析仪与实验室分析仪检测分析物（钠、氯、钾、尿素氮[UN]、肌酐、葡萄糖）的一致性水平。为健康成年猫的 POC 分析仪建立参考区间。
前瞻性观察性研究。
大学教学医院。
筛选了 55 只猫。由于采血时的攻击性而无法进行静脉切开术，有 7 只猫被排除在外，由于长时间的约束，有 1 只猫被排除在外；最终有 47 只猫被纳入研究。
无。
在该患者人群中，计算了 POC 分析仪的参考区间：钠 145-157mmol/L；氯 116-124mmol/L；钾 3.4-5.5mmol/L；UN 5.71-13.9mmol/L（16-39mg/dl）；肌酐 74.3-189.2mmol/L（0.84-2.14mg/dl）；葡萄糖 4-11.8mmol/L（72-213mg/dl）。使用 Bland-Altman 法比较 POC 分析仪和实验室分析仪。每个分析物的偏差如下：钠 1.55mmol/L；氯 0.99mmol/L；钾 0.21mmol/L；UN -0.25mmol/L（-0.7mg/dl）；肌酐 9.73mmol/L（0.11mg/dl）；葡萄糖 0.5mmol/L（9.79mg/dl）。
每个分析物的参考区间与其他化学分析仪相似。POC 分析仪和实验室分析仪在分析 UN 时无显著差异，钠、钾、氯、肌酐和葡萄糖则有统计学显著差异。然而，这些差异值可能不足以改变患者治疗的初始临床决策。
