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幼鼠肾上腺多巴胺β-羟化酶的诱导:甲状腺激素的影响

Adrenal dopamine beta-hydroxylase induction in the young rat: influence of thyroid hormones.

作者信息

Gripois D, Valens M

出版信息

Mol Cell Endocrinol. 1986 Apr;45(1):77-80. doi: 10.1016/0303-7207(86)90085-7.

Abstract

The adrenals of 14-day-old control and hypothyroid rats have been stimulated by insulin-induced hypoglycaemia, and the subsequent induction in dopamine beta-hydroxylase (DBH) has been studied. In control rats, DBH induction was maximum 48 h after insulin administration. Hypothyroidism completely suppressed DBH induction.

摘要

通过胰岛素诱导的低血糖刺激14日龄对照大鼠和甲状腺功能减退大鼠的肾上腺,并研究随后多巴胺β-羟化酶(DBH)的诱导情况。在对照大鼠中,胰岛素给药后48小时DBH诱导达到最大值。甲状腺功能减退完全抑制了DBH诱导。

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