School of mechanical and electrical engineering, Nanchang University, Nanchang 330031, China.
College of chemistry, Nanchang University, Nanchang 330031, China.
Spectrochim Acta A Mol Biomol Spectrosc. 2022 May 5;272:120956. doi: 10.1016/j.saa.2022.120956. Epub 2022 Jan 29.
Antibiotic residues have become a public health issues, the fast detection of tetracycline (Tc) in the environment is urgently required. In this work, TiC quantum dots (TiC QDs) and Europium ions jointly constructed a ratiometric fluorescence (FL) platform for the detection of Tc, based on synergistic impact of the Foster Resonance Energy Transfer (FRET) from TiC QDs to Eu ions and the Antenna Effect (AE) between Tc and Eu ions. And we proposed a ratiometric FL platform for detecting Tc with good linear response range (100-1000 uM) and low detection limit (48.79 nM). Meanwhile, we applied this platform to detect a serious of β-diketone ligands of Eu ions, demonstrating the platform's versatility for this category of chemical. Furthermore, based on the color changes of QDs@Eu from blue to red at 365 nm ultraviolet light, an intelligent detection smart device was built for the visual semi-quantitative detection of Tc in actual samples. We proved the applicability of the device in complicated samples and the potential for rapid, sensitive, intuitive and point-of-care detection in the field of environment, food, pharmaceutical and agriculture.
抗生素残留已成为公共卫生问题，因此迫切需要快速检测环境中的四环素（Tc）。在这项工作中，基于 TiC 量子点（TiC QDs）到 Eu 离子的Förster 共振能量转移（FRET）和 Tc 与 Eu 离子之间的天线效应（AE）的协同影响，TiC 量子点和 Eu 离子共同构建了比率荧光（FL）平台，用于检测 Tc。并且我们提出了一种比率 FL 平台，用于检测 Tc，具有良好的线性响应范围（100-1000 μM）和低检测限（48.79 nM）。同时，我们将该平台应用于检测一系列 Eu 离子的β-二酮配体，证明了该平台对这一类化学物质的通用性。此外，基于 365nm 紫外光下 QDs@Eu 从蓝色变为红色的颜色变化，构建了一种智能检测智能设备，用于实际样品中 Tc 的可视化半定量检测。我们证明了该设备在复杂样品中的适用性以及在环境、食品、医药和农业领域中快速、灵敏、直观和现场检测的潜力。
