Henan Key Laboratory of Diamond Optoelectronic Materials and Devices, Key Laboratory of Material Physics, Ministry of Education, School of Physics and Microelectronics, Zhengzhou University, Zhengzhou 450001, China.
Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
Spectrochim Acta A Mol Biomol Spectrosc. 2021 Oct 5;259:119901. doi: 10.1016/j.saa.2021.119901. Epub 2021 May 4.
An europium functionalized ZnO quantum dots (QDs) ratiometric fluorescent nanoprobe is designed to establish a real time, on-site visual, and highly sensitive probe method for tetracycline (TC). The yellow-emitting ZnO QDs serves as the internal reference, while the Eu chelated on the surface of ZnO QDs is used as the signal reporting unit. This nanoprobe exhibits rapid response, excellent selectivity, and high sensitivity with a detection limit of 4 nM in detecting the levels of TC. In addition, fluorescence of the nanoprobe can change from yellow to red as the concentration of TC increases. Thus, naked eye detection of TC was realized using the test paper processed by nanoprobe, followed by RGB value analysis function on the mobile phone APP.
设计了一种铕功能化 ZnO 量子点（QDs）比率荧光纳米探针，用于建立四环素（TC）的实时、现场可视化和高灵敏度探针方法。发射黄色荧光的 ZnO QDs 用作内参，而表面螯合的 Eu 则用作信号报告单元。该纳米探针具有快速响应、优异选择性和高灵敏度，检测 TC 的检出限低至 4 nM。此外，随着 TC 浓度的增加，纳米探针的荧光从黄色变为红色。因此，通过用纳米探针处理的试纸实现了 TC 的肉眼检测，然后通过手机 APP 的 RGB 值分析功能进行分析。
