Department of Health Care and Sports, Faculty of Human Life Design, Toyo University, 1-7-11, Akabanedai, Kita-ku, Tokyo 115-0053, Japan; Department of Sports Sciences, Japan Institute of Sports Sciences, 3-15-1 Nishigaoka, Kita-ku, Tokyo 115-0056, Japan.
Department of Sports Sciences, Japan Institute of Sports Sciences, 3-15-1 Nishigaoka, Kita-ku, Tokyo 115-0056, Japan.
Growth Horm IGF Res. 2022 Apr;63:101445. doi: 10.1016/j.ghir.2022.101445. Epub 2022 Feb 2.
Hyperoxic gas inhalation during exercise may negatively affect all-out sprint interval exercise (SIE)-induced hormonal, metabolic, and angiogenic responses. We investigated the effects of acute all-out SIE under systemic hyperoxia on hormonal, metabolic, and angiogenic responses.
This was a randomised-crossover trial. Ten healthy males (mean ± standard error of age = 23.1 ± 0.9 years; height = 171.0 ± 1.6 cm; body mass = 66.2 ± 2.0 kg; body mass index = 22.6 ± 0.5 kg/m) completed the following two experimental regimens: 1) SIE under normoxia and 2) SIE under systemic hyperoxia (FiO = 60%). The subjects performed four bouts of 30-s maximal cycling efforts with 4 min recovery between efforts. The circulating levels of hormonal (growth hormone, epinephrine, and norepinephrine), metabolic (glucose, free fatty acid, and lactate), and angiogenic (vascular endothelial growth factor, matrix metalloproteinase-2 and -9, and endostatin) markers were measured before and at 0 (immediately after the regimen), 30, and 120 min after both regimens.
In response to both SIE regimens, the peak and mean power outputs gradually decreased over the intermittent exercise session compared with those in the first bout (p < 0.01) with no significant differences between the regimens. Both regimens significantly increased the circulating concentrations of all hormonal, metabolic, and angiogenic markers (p < 0.01). However, there were no significant differences in the levels of these markers in response to the two regimens at any time point (p > 0.05).
These findings suggest that acute systemic hyperoxia does not influence the hormonal, metabolic, and angiogenic responses to all-out SIE.
运动时吸入高浓度氧气可能会对全力冲刺间歇训练（SIE）引起的激素、代谢和血管生成反应产生负面影响。我们研究了在全身高氧环境下进行急性全力 SIE 对激素、代谢和血管生成反应的影响。
这是一项随机交叉试验。10 名健康男性（平均年龄±标准误差=23.1±0.9 岁；身高=171.0±1.6 厘米；体重=66.2±2.0 公斤；体重指数=22.6±0.5 公斤/米）完成了以下两种实验方案：1）在常氧下进行 SIE，2）在全身高氧（FiO=60%）下进行 SIE。受试者进行了四组 30 秒最大自行车运动，每组之间休息 4 分钟。在两种方案之前和之后的 0（方案后立即）、30 和 120 分钟测量了激素（生长激素、肾上腺素和去甲肾上腺素）、代谢（葡萄糖、游离脂肪酸和乳酸）和血管生成（血管内皮生长因子、基质金属蛋白酶-2 和 -9 以及内皮抑素）标志物的循环水平。
对于两种 SIE 方案，与第一回合相比，间歇性运动过程中峰值和平均功率输出逐渐下降（p<0.01），两种方案之间没有差异。两种方案均显著增加了所有激素、代谢和血管生成标志物的循环浓度（p<0.01）。然而，在任何时间点，两种方案对这些标志物的水平都没有显著差异（p>0.05）。
这些发现表明，急性全身高氧不会影响全力 SIE 的激素、代谢和血管生成反应。
