Manferdelli Giorgio, Freitag Nils, Doma Kenji, Hackney Anthony C, Predel Hans-Georg, Bloch Wilhelm, Schumann Moritz
Institute of Cardiovascular Research and Sport Medicine, Department of Molecular and Cellular Sport Medicine, German Sport University, Cologne, Germany.
Sport and Exercise Science, James Cook University, Townsville, QLD, Australia.
J Hum Kinet. 2020 Jul 21;73:125-134. doi: 10.2478/hukin-2019-0137. eCollection 2020 Jul.
This study aimed to compare selected hormonal responses to a single session of high intensity interval training performed with an increased fraction of inspired oxygen (hyperoxia) and under normoxic conditions. Twelve recreationally trained men (age 24 ± 3 years) performed two sessions of high intensity interval training on a cycle ergometer, in randomized order with hyperoxia (4 L·min with a flowrate of 94% O) and normoxia. Each session consisted of 5 intervals of 3 minutes at 85% of the maximal power output, interspersed by 2 min at 40% of the maximal power output. Serum cortisol, prolactin and vascular endothelial growth factor (VEGF) were assessed both before and immediately after each high intensity interval training session. Statistically significant differences in cortisol were found between hyperoxic and normoxic conditions (p = 0.011), with a significant increase in hyperoxia (61.4 ± 73.2%, p = 0.013, ES = -1.03), but not in normoxia (-1.3 ± 33.5%, p > 0.05, ES = 0.1). Prolactin increased similarly in both hyperoxia (118.1 ± 145.1%, p = 0.019, ES = -0.99) and normoxia (62.14 ± 75.43%, p = 0.005, ES = -0.5). VEGF was not statistically altered in either of the conditions. Our findings indicate that a single session of high intensity interval training in low-dose hyperoxia significantly increased cortisol concentrations in recreationally trained individuals compared to normoxia, while the difference was smaller in prolactin and diminished in VEGF concentrations.
本研究旨在比较在吸入氧分数增加（高氧）和常氧条件下进行单次高强度间歇训练后，选定的激素反应。12名受过休闲训练的男性（年龄24±3岁）在自行车测力计上进行了两次高强度间歇训练，以随机顺序分别在高氧（4L·min，氧流量94%）和常氧条件下进行。每次训练包括5个3分钟的间隔，强度为最大功率输出的85%，中间穿插2分钟最大功率输出40%的时段。在每次高强度间歇训练前后均评估血清皮质醇、催乳素和血管内皮生长因子（VEGF）。发现高氧和常氧条件下皮质醇存在统计学显著差异（p = 0.011），高氧时显著增加（61.4±73.2%，p = 0.013，效应量ES = -1.03），而常氧时无显著增加（-1.3±33.5%，p>0.05，效应量ES = 0.1）。高氧（118.1±145.1%，p = 0.019，效应量ES = -0.99）和常氧（62.14±75.43%，p = 0.005，效应量ES = -0.5）时催乳素增加情况相似。两种条件下VEGF均无统计学改变。我们的研究结果表明，与常氧相比，在低剂量高氧条件下进行单次高强度间歇训练可使受过休闲训练的个体皮质醇浓度显著增加，而催乳素的差异较小，VEGF浓度差异不明显。
