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肯尼亚内罗毕一家美沙酮治疗诊所就诊患者中使用大麻的流行率和模式。

The prevalence and pattern of cannabis use among patients attending a methadone treatment clinic in Nairobi, Kenya.

机构信息

Department of Psychiatry, Mathari National Teaching and Referral Hospital, Nairobi, Kenya.

Department of Psychiatry, Mbagathi Hospital, Nairobi, Kenya.

出版信息

Subst Abuse Treat Prev Policy. 2022 Feb 15;17(1):12. doi: 10.1186/s13011-022-00437-7.

DOI:10.1186/s13011-022-00437-7
PMID:35168646
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8845270/
Abstract

BACKGROUND

Cannabis use during methadone treatment may negatively impact treatment outcomes. The aim of this study was to determine the prevalence and pattern of cannabis use among patients attending a methadone treatment clinic in Nairobi, Kenya.

METHODS

This was a retrospective study of 874 patients on methadone therapy at a methadone maintenance treatment clinic in Nairobi, Kenya from December 2014 to November 2018. Data on sociodemographic characteristics and drug use patterns based on urine drug screens was collected from patient files. Data was analyzed using Statistical Package for the Social Sciences (SPSS) for windows version 23.0.

RESULTS

Point prevalence of cannabis use was 85.8% (95% CI, 83.3 - 88.0) at baseline and 62.7% (95% CI, 59.5 - 65.8) during follow-up. A pattern of polysubstance use was observed where opioids, cannabis and benzodiazepines were the most commonly used drugs. The mean age of the patients was 35.3 (SD 9.0) years with the majority being male, unemployed (76%), (51.4%) had reached primary level of education, and (48.5%) were divorced or separated. University education was associated with reduced risk for cannabis use OR = 0.1 (95% CI, 0.02-0.8, p = 0.031).

CONCLUSION

Cannabis use is prevalent among patients attending a methadone treatment clinic in Kenya, suggesting need for targeted interventions to address the problem of cannabis use during methadone treatment.

摘要

背景

在美沙酮治疗期间使用大麻可能会对治疗结果产生负面影响。本研究旨在确定肯尼亚内罗毕一家美沙酮治疗诊所的患者中使用大麻的流行率和模式。

方法

这是一项回顾性研究,纳入了 2014 年 12 月至 2018 年 11 月期间在肯尼亚内罗毕一家美沙酮维持治疗诊所接受美沙酮治疗的 874 名患者。从患者档案中收集了社会人口统计学特征和基于尿液药物筛查的药物使用模式的数据。使用统计软件包(SPSS)进行数据分析。

结果

基线时大麻使用率为 85.8%(95%置信区间,83.3-88.0),随访期间为 62.7%(95%置信区间,59.5-65.8)。观察到多物质使用模式,其中阿片类药物、大麻和苯二氮䓬类药物是最常使用的药物。患者的平均年龄为 35.3 岁(标准差 9.0),大多数为男性,失业(76%),(51.4%)达到了小学水平教育,(48.5%)离婚或分居。大学教育与大麻使用的风险降低相关,OR=0.1(95%置信区间,0.02-0.8,p=0.031)。

结论

在肯尼亚的美沙酮治疗诊所中,使用大麻的患者较为普遍,这表明需要针对美沙酮治疗期间使用大麻的问题采取有针对性的干预措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe19/8845270/fdecc1b79691/13011_2022_437_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe19/8845270/fdecc1b79691/13011_2022_437_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe19/8845270/fdecc1b79691/13011_2022_437_Fig1_HTML.jpg

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