Suppr超能文献

无线 USB 样电化学平台,用于微滴中的单个电化学传感。

Wireless USB-like electrochemical platform for individual electrochemical sensing in microdroplets.

机构信息

School of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen, Guangdong, 518060, PR China.

Shenzhen Refresh Intelligent Technology Co.,Ltd. Shenzhen, Guangdong, 518000, PR China.

出版信息

Anal Chim Acta. 2022 Mar 8;1197:339526. doi: 10.1016/j.aca.2022.339526. Epub 2022 Jan 20.

Abstract

The portable electrochemical platform can adapt to more usage scenarios, which is essential for drug discovery, toxicology, and cell biology. Here, we constructed the wireless USB-like electrochemical platform for simultaneous multi-channel electrochemical sensing in microdroplet array. On such platform, multi-channel mini-pillar arrays can anchor reagent droplet (a few microliters to dozens of microliters), and the wireless USB-like electrochemical platform can achieve simultaneously multi-channel detection. As a concept-of-proof for multi-channel, the 4∗4 channels are chosen as a model to proof the practicality of such portable electrochemical platform, the relative standard deviation (RSD) of such a platform in microdroplets sensing is below 5% level. The quantitative electrochemical analysis of multiple glucose concentrations in miniature workstation was also achieved, and only 0.97% difference between traditional electrochemical workstation. The wireless USB-like electrochemical platform with the characteristics of cloud data management and multi-channel, which enables remote detection and analysis and presents an opportunity for future portable high-throughput biomedical applications.

摘要

该便携式电化学平台可适应更多的使用场景,这对药物发现、毒理学和细胞生物学至关重要。在这里,我们构建了用于微滴阵列中同时多通道电化学传感的无线 USB 样电化学平台。在该平台上,多通道迷你柱阵列可以固定试剂液滴(数微升至数十微升),而无线 USB 样电化学平台可以实现同时多通道检测。作为多通道的概念验证,选择 4*4 通道作为模型来证明这种便携式电化学平台的实用性,该平台在微滴检测中的相对标准偏差(RSD)低于 5%。还实现了微型工作站中多个葡萄糖浓度的定量电化学分析,与传统电化学工作站相比仅相差 0.97%。这种具有云数据管理和多通道功能的无线 USB 样电化学平台,可实现远程检测和分析,为未来的便携式高通量生物医学应用提供了机会。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验