University of Texas at Southwestern School of Medicine, Dallas, TX.
Boston University School of Medicine, Boston, MA.
J Hand Surg Am. 2022 Apr;47(4):341-347. doi: 10.1016/j.jhsa.2021.12.005. Epub 2022 Feb 12.
The treatment of ganglion cysts of the wrist remains understudied in the pediatric population, with the literature showing variable recurrence rates following different interventions. This study sought to determine whether surgical and nonsurgical management of pediatric ganglion cysts was associated with improved resolution rates when compared to observation alone.
We identified 654 cases of pediatric ganglion cysts treated across 5 institutions between 2012 and 2017. The mean age at presentation was 11.6 ± 5.2 years. Of the patients, 315 had >2 years (mean, 50.0 months) of follow-up, either via chart review or telephone callbacks. There were 4 different treatment groups: (1) observation, (2) cyst aspiration, (3) removable orthosis, and (4) surgical excision.
For patients followed >2 years, the cyst resolved in 44% (72/163) of those observed. Only 18% (9/49) of those treated with aspiration resolved, and 55% (12/22) of those treated with an orthosis resolved. Surgical excision was associated with resolution of the cyst in 73% (59/81) of patients. Observation had higher rates of resolution compared to aspiration. Orthosis fabrication and observation had similar rates of cyst resolution. Surgery had the highest rates of resolution when compared to observation and aspiration. Patients older than 10 years were less likely to have the cyst resolve with observation (35%; 28/80) than those younger than 10 years (53%; 44/83) at >2 years of follow-up.
This study did not find evidence that nonsurgical treatments were associated with improved rates of cyst resolution compared to observation alone in a large pediatric sample. Surgical excision had the overall highest rate of resolution. Despite the costs and increased clinic time of orthosis fabrication and aspiration, these treatments were not associated with improved rates of cyst resolution in pediatric ganglion cysts compared to observation, with aspiration having higher rates of recurrence compared to observation.
TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic IV.
在儿科人群中,腕部神经腱鞘囊肿的治疗仍研究不足,文献显示不同干预措施后的复发率各不相同。本研究旨在确定与单独观察相比,手术和非手术治疗小儿神经腱鞘囊肿是否与更高的缓解率相关。
我们在 2012 年至 2017 年间在 5 家机构共确定了 654 例小儿神经腱鞘囊肿患者。发病时的平均年龄为 11.6±5.2 岁。其中 315 例患者的随访时间超过 2 年(平均 50.0 个月),通过病历回顾或电话随访。有 4 种不同的治疗组:(1)观察,(2)囊肿抽吸,(3)可移除矫形器,和(4)手术切除。
对于随访时间超过 2 年的患者,在观察组中,囊肿缓解率为 44%(72/163)。仅在抽吸组中,18%(9/49)的患者缓解,在矫形器组中,55%(12/22)的患者缓解。在手术组中,73%(59/81)的患者囊肿得到缓解。观察组的缓解率高于抽吸组。矫形器制作和观察组的囊肿缓解率相似。与观察和抽吸相比,手术组的缓解率最高。10 岁以上的患者在随访 2 年以上时,囊肿缓解的可能性低于 10 岁以下的患者(35%,28/80 比 53%,44/83)。
本研究在一个大型儿科样本中未发现非手术治疗与单独观察相比,能提高囊肿缓解率的证据。手术切除总体上具有最高的缓解率。尽管矫形器制作和抽吸的成本和增加的就诊时间,但与观察相比,这些治疗方法并不能提高小儿神经腱鞘囊肿的囊肿缓解率,抽吸的复发率高于观察。
研究类型/证据水平:治疗性 IV 级。