A Review of Soft Tissue and Nerve Masses in the Pediatric Hand: Pathology, Diagnosis, and Management Strategies.

Soft tissue and nerve masses of the pediatric hand, though often benign, prompt significant concern due to their visible location, potential for functional impact, and diagnostic uncertainty. Compared to adults, children demonstrate a distinct spectrum of hand lesions, with differences in prevalence, presentation, and pathology. Given the unique considerations in pediatric evaluation, including developmental anatomy and the importance of a child-appropriate approach to physical examination, clinicians must be equipped with a clear understanding of these lesions to guide appropriate management. This review synthesizes current literature on the pathology, diagnosis, and treatment of common pediatric hand masses, including cysts, lipomas, giant cell tumors, vascular tumors, and peripheral nerve lesions. By consolidating available evidence and expert recommendations, this article aims to support accurate clinical assessment and optimize care for pediatric patients presenting with soft tissue and nerve masses.