School of Psychology, Trinity College Dublin, Dublin, Ireland.
Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland.
Nat Commun. 2022 Feb 15;13(1):870. doi: 10.1038/s41467-022-28513-3.
Network theory of mental illness posits that causal interactions between symptoms give rise to mental health disorders. Increasing evidence suggests that depression network connectivity may be a risk factor for transitioning and sustaining a depressive state. Here we analysed social media (Twitter) data from 946 participants who retrospectively self-reported the dates of any depressive episodes in the past 12 months and current depressive symptom severity. We construct personalised, within-subject, networks based on depression-related linguistic features. We show an association existed between current depression severity and 8 out of 9 text features examined. Individuals with greater depression severity had higher overall network connectivity between depression-relevant linguistic features than those with lesser severity. We observed within-subject changes in overall network connectivity associated with the dates of a self-reported depressive episode. The connectivity within personalized networks of depression-associated linguistic features may change dynamically with changes in current depression symptoms.
精神疾病的网络理论假设,症状之间的因果相互作用导致了心理健康障碍。越来越多的证据表明,抑郁网络连通性可能是向抑郁状态转变和维持的一个风险因素。在这里,我们分析了来自 946 名参与者的社交媒体(Twitter)数据,这些参与者回顾性地报告了过去 12 个月中任何抑郁发作的日期和当前抑郁症状的严重程度。我们基于与抑郁相关的语言特征构建了个性化的、个体内的网络。我们发现当前抑郁严重程度与 9 个文本特征中的 8 个之间存在关联。与严重程度较低的个体相比,抑郁严重程度较高的个体在与抑郁相关的语言特征之间的整体网络连通性更高。我们观察到与自我报告的抑郁发作日期相关的整体网络连通性的个体内变化。与当前抑郁症状变化相关的,与抑郁相关的语言特征的个性化网络中的连通性可能会发生动态变化。