Sano Madoka, Murai Ryosuke, Kim Kitae, Furukawa Yutaka
Department of Cardiovascular Medicine, Kobe City Medical Center General Hospital, Kobe, Japan.
J Cardiol Cases. 2022 Jul;26(1):17-20. doi: 10.1016/j.jccase.2022.01.015. Epub 2022 Feb 11.
There is increasing evidence for myocarditis as a complication of the mRNA coronavirus disease 2019 (COVID-19) vaccination. We report the case of a 20-year-old previously healthy man who presented with fever and chest pain 2 days after the second dose of mRNA-1273 vaccine. Electrocardiogram and laboratory studies showed extensive ST-segment elevation accompanied by elevated cardiac biomarkers. Cardiac magnetic resonance (CMR) revealed late gadolinium enhancement (LGE) characteristics of myocarditis. The patient rapidly improved with conservative management and was discharged on hospital day 6. As an advantage over previous reports, we performed a 1-month follow-up CMR. It showed improvement in myocardial edema but persistence of LGE which may indicate irreversible fibrosis. CMR may be useful not only for diagnosis but also for prognostic evaluation of myocarditis after COVID-19 mRNA vaccination. < With the expansion of coronavirus disease 2019 (COVID-19) vaccine administration, the number of cases of myocarditis as a complication has been increasing. Cardiac magnetic resonance imaging can be useful for the diagnosis and follow-up of patients with myocarditis after mRNA COVID-19 vaccination. Persistent late gadolinium enhancement may indicate irreversible myocardial fibrosis, and it is also associated with poor prognosis, similar to previously reported cases of other acute myocarditis.>.
越来越多的证据表明,心肌炎是2019年冠状病毒病(COVID-19)mRNA疫苗接种后的一种并发症。我们报告了一例20岁既往健康男性的病例,该患者在接种第二剂mRNA-1273疫苗后2天出现发热和胸痛。心电图和实验室检查显示广泛的ST段抬高,并伴有心脏生物标志物升高。心脏磁共振成像(CMR)显示出心肌炎的晚期钆增强(LGE)特征。该患者经保守治疗后迅速好转,并于住院第6天出院。与之前的报告相比,我们进行了为期1个月的CMR随访。结果显示心肌水肿有所改善,但LGE持续存在,这可能表明存在不可逆的纤维化。CMR不仅可能有助于心肌炎的诊断,还可用于COVID-19 mRNA疫苗接种后心肌炎的预后评估。<随着2019年冠状病毒病(COVID-19)疫苗接种范围的扩大,作为并发症的心肌炎病例数量一直在增加。心脏磁共振成像对于mRNA COVID-19疫苗接种后心肌炎患者的诊断和随访可能有用。持续的晚期钆增强可能表明存在不可逆的心肌纤维化,并且与预后不良相关,这与之前报道的其他急性心肌炎病例类似。>