Elliott T S, Ispahani P, Cowlishaw W A
J Antimicrob Chemother. 1986 Feb;17(2):245-50. doi: 10.1093/jac/17.2.245.
A combination of gentamicin and ceftazidime was used to treat four neonates with Gram-negative bacillary meningitis. The causative organisms were Escherichia coli (3 cases) and Enterobacter agglomerans (1 case). The laboratory findings, including cerebrospinal fluid (CSF) ceftazidime levels and bactericidal activity demonstrated that penetration of the cephalosporin into the cerebrospinal fluid was adequate. The antibiotics caused no side effects and all the patients responded well. On follow up none of the patients exhibited neurological deficits.
庆大霉素和头孢他啶联合用于治疗4例革兰氏阴性杆菌脑膜炎新生儿。致病菌为大肠杆菌（3例）和聚团肠杆菌（1例）。实验室检查结果，包括脑脊液（CSF）中头孢他啶水平和杀菌活性表明，头孢菌素在脑脊液中的渗透是足够的。抗生素未引起副作用，所有患者反应良好。随访时，所有患者均未出现神经功能缺损。
