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2019 年波兰的乙型肝炎。

Hepatitis B in Poland in 2019.

机构信息

National Institute of Public Health NIH - National Research Institute, \Department of Epidemiology of Infectious Diseases and Surveillance.

出版信息

Przegl Epidemiol. 2021;75(3):367-378. doi: 10.32394/pe.75.34.

Abstract

OBJECTIVE

Assessment of hepatitis B epidemiological situation in Poland in 2019 compared to previous years.

MATERIAL AND METHODS

Data on the incidence of hepatitis B and HBV infections from 2019 registered by sanitary and epidemiological stations in the electronic Epidemiological Interview Registration System in Poland were analyzed. Data from the published annual bulletins: "Infectious diseases and poisonings in Poland" and "Vaccinations in Poland" were also used. Data on deaths were obtained from the Central Statistical Office.

RESULTS

In 2019, 2,854 cases of hepatitis B were reported, which corresponds to the incidence of 7.4 per 100,000 population. Acute cases accounted for 1.6% of all registered cases. The incidence of acute hepatitis B was higher by 20% than in 2018 and lower by 20% than the median incidence for 2013-2017. There were no acute cases among children and adolescents aged 0-19 years. In the age group 20-24, 1 case was reported. The incidence of chronic and unknown stage of hepatitis B was lower by 11% than in the previous year, however, compared to the median incidence of chronic hepatitis B in 2013-2017, it was lower by 15%. As in previous years, acute, chronic and unknown infections occurred more often among men than among women, and more often among urban than rural residents. The most common and probable routes of HBV infections were medical procedures, which accounted for 75% of cases with a known route of transmission. In 2019, the HBV vaccination coverage with the third vaccine dose in children born in 2018 was 90.5%, which is less than in previous year. In 2019, 29 people died due to hepatitis B, including one as a result of an acute infection.

CONCLUSIONS

The incidence of hepatitis B in Poland over the years (2015-2019) has a decreasing tendency. Among people covered by universal HBV vaccinations, born after 1994, no acute cases were reported. However, the decrease in newborns and infants vaccination coverage may cause the increased risk of new HBV infections, even in the people subject to compulsory vaccinations against hepatitis B. Changes introduced in the surveillance system on hepatitis B in 2014 allow for the levelling of territorial discrepancies in the hepatitis B registered cases and allow for the assessment of the actual number of newly detected HBV infections. The persistence of the low incidence of acute hepatitis B indicates the need to maintain the preventive measures applied so far, in particular the universal compulsory vaccinations of newborns and recommending vaccinations to all previously unvaccinated people.

摘要

目的

评估 2019 年波兰乙型肝炎的流行病学情况与前几年相比的变化。

材料与方法

分析了 2019 年波兰卫生和流行病学站在电子传染病访谈登记系统中登记的乙型肝炎和乙型肝炎病毒感染发病率数据。还使用了已发布的年度公告:“波兰传染病和中毒”和“波兰疫苗接种”。死亡数据来自中央统计局。

结果

2019 年报告了 2854 例乙型肝炎病例,发病率为每 10 万人 7.4 例。急性病例占所有登记病例的 1.6%。急性乙型肝炎的发病率比 2018 年高 20%,比 2013-2017 年的中位数发病率低 20%。0-19 岁的儿童和青少年中没有急性病例。在 20-24 岁年龄组中报告了 1 例。慢性和未知阶段乙型肝炎的发病率比前一年低 11%,但与 2013-2017 年慢性乙型肝炎的中位数发病率相比,仍低 15%。与前几年一样,急性、慢性和未知感染在男性中比女性更常见,在城市居民中比农村居民更常见。最常见和可能的乙型肝炎病毒感染途径是医疗程序,占已知传播途径病例的 75%。2019 年,2018 年出生的儿童第三次乙肝疫苗接种覆盖率为 90.5%,低于前一年。2019 年,有 29 人死于乙型肝炎,其中 1 人死于急性感染。

结论

波兰乙型肝炎的发病率多年来(2015-2019 年)呈下降趋势。在普遍接受乙型肝炎疫苗接种、1994 年后出生的人群中,未报告急性病例。然而,新生儿和婴儿疫苗接种覆盖率的下降可能导致新的乙型肝炎病毒感染风险增加,即使在强制接种乙型肝炎疫苗的人群中也是如此。2014 年乙型肝炎监测系统的改革允许在登记的乙型肝炎病例中消除地域差异,并评估新发现的乙型肝炎病毒感染的实际数量。急性乙型肝炎发病率持续较低表明需要保持迄今为止采取的预防措施,特别是对新生儿的普遍强制性疫苗接种,并建议所有以前未接种疫苗的人接种疫苗。

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