Silveira Ana Karina Téles, Lynch Maria Isabel, Medeiros Clistenes Stênio Lima De, Moraes Bruno Teixeira De, Remígio Maria Cecília, Paiva Michelle Maria Figueiredo, Silva Renata Ribeiro, Torres Virgínia Laura Lucas
Head and Neck Division, Ophthalmology Department, Hospital das Clínicas, Universidade Federal de Pernambuco, Recife, PE, Brazil.
Head and Neck Division, Otorhinolaryngology Department, Hospital das Clínicas, Universidade Federal de Pernambuco, Recife, PE, Brazil.
Arq Bras Oftalmol. 2022 Feb 14;85(6):614-619. doi: 10.5935/0004-2749.20220083. eCollection 2022.
This study evaluated the frequency of the most common ophthalmological, neurological, and systemic findings in symptomatic patients seen at a COVID-19 screening service at Hospital das Clínicas - Universidade Federal de Pernambuco.
A total of 104 patients under clinical suspicion of SARS-CoV-2 infection underwent medical evaluation through an ophthalmological and systemic symptoms survey. All participants selected for the study underwent COVID-19 RT-PCR testing.
The mean age was 38.8 years, with 44.23% between 31 and 40 years old, 68.27% female, and 31.73% male. The most common symptoms in patients with a positive RT-PCR test were cough (69.23%), fever (42.3%), hyposmia (38.46%), myalgia (38.46%), and ageusia (30.77%). In the positive group, 34.61% presented with ophthalmological symptoms: burning (19.23%), eye pain (11.54%), foreign body sensation (7.7%), hyperemia (7.7%), and tearing (3.84%).
Systemic clinical features were characteristic of upper respiratory infection, but neurological findings of hyposmia and anosmia proved to be important markers for suspicion of SARS-CoV-2 infection. Ophthalmic symptoms in patients with COVID-19 were similar to those observed in other viral conditions and may precede systemic conditions. A high rate of self-medication was observed for general symptoms compared with ophthalmological conditions.
本研究评估了在伯南布哥联邦大学临床医院的新冠病毒筛查服务中，有症状患者最常见的眼科、神经科和全身检查结果的出现频率。
共有104名临床怀疑感染SARS-CoV-2的患者通过眼科和全身症状调查接受了医学评估。所有入选该研究的参与者均接受了新冠病毒RT-PCR检测。
平均年龄为38.8岁，其中31至40岁的占44.23%，女性占68.27%，男性占31.73%。RT-PCR检测呈阳性的患者中最常见的症状为咳嗽（69.23%）、发热（42.3%）、嗅觉减退（38.46%）、肌痛（38.46%）和味觉减退（30.77%）。在阳性组中，34.61%的患者出现眼科症状：烧灼感（19.23%）、眼痛（11.54%）、异物感（7.7%）、充血（7.7%）和流泪（3.84%）。
全身临床特征为上呼吸道感染的特点，但嗅觉减退和嗅觉丧失的神经学检查结果被证明是怀疑感染SARS-CoV-2的重要标志。新冠病毒感染患者的眼部症状与其他病毒感染情况中观察到的症状相似，且可能先于全身症状出现。与眼科疾病相比，一般症状的自我用药率较高。
