Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Med Phys. 2022 Apr;49(4):2836-2845. doi: 10.1002/mp.15534. Epub 2022 Mar 3.
In recent years, multi-parametric magnetic resonance imaging (MpMRI) has played a major role in radiation therapy treatment planning. The superior soft tissue contrast, functional or physiological imaging capabilities, and the flexibility of site-specific image sequence development has placed MpMRI at the forefront. In this article, the present status of MpMRI for external beam radiation therapy planning is reviewed. Common MpMRI sequences, preprocessing, and quality assurance strategies are briefly discussed, and various image registration techniques and strategies are addressed. Image segmentation methods including automatic segmentation and deep learning techniques for organs at risk and target delineation are reviewed. Due to the advancement in MRI-guided online adaptive radiotherapy, treatment planning considerations addressing MRI only planning are also discussed.
近年来，多参数磁共振成像（MpMRI）在放射治疗计划中发挥了重要作用。其优越的软组织对比度、功能或生理成像能力以及特定部位图像序列开发的灵活性使其处于领先地位。本文综述了外束放射治疗计划中 MpMRI 的现状。简要讨论了常见的 MpMRI 序列、预处理和质量保证策略，并介绍了各种图像配准技术和策略。本文还回顾了用于危及器官和靶区勾画的自动分割和深度学习技术等图像分割方法。由于 MRI 引导在线自适应放疗的进步，本文还讨论了仅基于 MRI 计划的治疗计划考虑因素。
