Yang Xudong, Wang Yali, Liu Yongping, Shang Lei, Cheng Zhijian, Fang Liping, Zhang Jian, Feng Yifan, Zhang Kuiwei, Jiang Shanjiao, He Xijing
Department of Neurorehabilitation, Xi'an International Medical Center Hospital Xi'an 710100, Shaanxi Province, China.
Department of Rehabilitation, Xi'an International Medical Center Hospital Xi'an 710100, Shaanxi Province, China.
Am J Transl Res. 2022 Jan 15;14(1):501-510. eCollection 2022.
Traditional Chinese medicine has been reported to be effective in the treatment of epidemic diseases. Here, we aimed to investigate the effects of combined therapy of Chinese and western medicine on coronavirus disease 2019 (COVID-19).
A total of 60 patients diagnosed with COVID-19 were enrolled. Both the ordinary and severely affected patients were randomly divided into Groups A-C each with 10 cases each. The patients in Group A-C received Western medicine, Western medicine + traditional Chinese medicine, and Western medicine + traditional Chinese medicine + high dose of vitamin C, respectively. The time of disease recovery, symptoms disappearance, chest CT improvement, and tongue amelioration was recorded. Leukocyte, neutrophil and lymphocyte were monitored, as well as C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), procalitonin (PCT), inflammatory factors, partial pressure of oxygen and carbon dioxide (PaCO) and oxygenation index (PaO). Urinary tract stones, liver function, and other side-effects such as gastrointestinal dysfunction were also investigated.
Traditional Chinese medicine enhanced the effect of Western medicine, including the reduction of CRP, ESR, PCT, and inflammatory factors, and the increase of leukocyte, neutrophil, and lymphocyte counts, and the improvement of respiratory rate, PaO, PaCO, and oxygenation index. Traditional Chinese medicine combined with high-dose Vitamin C therapy more effectively shortened the time of disease recovery, symptom disappearance, chest CT improvement, and tongue amelioration.
a combined therapy of Western medicine, traditional Chinese medicine, and high dose of Vitamin C results in a most effective outcome in the treatment of COVID-19.
据报道,中药在治疗流行病方面具有疗效。在此,我们旨在研究中西医结合疗法对2019冠状病毒病(COVID-19)的影响。
共纳入60例确诊为COVID-19的患者。普通型和重型患者均随机分为A - C组,每组各10例。A - C组患者分别接受西药、西药 + 中药、西药 + 中药 + 高剂量维生素C治疗。记录疾病恢复时间、症状消失时间、胸部CT改善情况及舌象改善情况。监测白细胞、中性粒细胞和淋巴细胞,以及C反应蛋白(CRP)、红细胞沉降率(ESR)、降钙素原(PCT)、炎症因子、氧分压和二氧化碳分压(PaCO)及氧合指数(PaO)。还调查了尿路结石、肝功能以及胃肠道功能障碍等其他副作用。
中药增强了西药的疗效,包括降低CRP、ESR、PCT和炎症因子,增加白细胞、中性粒细胞和淋巴细胞计数,以及改善呼吸频率、PaO、PaCO和氧合指数。中药联合高剂量维生素C疗法更有效地缩短了疾病恢复时间、症状消失时间、胸部CT改善时间和舌象改善时间。
西药、中药和高剂量维生素C联合治疗在COVID-19治疗中产生最有效的结果。