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通过持续气道正压通气(CPAP)设备远程监测来检测阻塞性睡眠呼吸暂停患者的新冠病毒(COVID-19)及其他呼吸道感染

Detecting COVID-19 and other respiratory infections in obstructive sleep apnoea patients through CPAP device telemonitoring.

作者信息

Pépin Jean-Louis, Bailly Sébastien, Borel Jean-Christian, Logerot Sophie, Sapène Marc, Martinot Jean-Benoît, Lévy Patrick, Tamisier Renaud

机构信息

HP2 Laboratory, INSERM U1042, University Grenoble Alpes, Grenoble, France.

EFCR Laboratory, Grenoble Alpes University Hospital, Grenoble, France.

出版信息

Digit Health. 2021 Mar 26;7:20552076211002957. doi: 10.1177/20552076211002957. eCollection 2021 Jan-Dec.

Abstract

OBJECTIVE

The earliest possible detection of individuals with COVID-19 has been essential to curb the spread of infection. Existing digital tools have been scaled up to address this issue. Every night telemonitoring data on continuous positive airway pressure (CPAP) device use, the first-line therapy for obstructive sleep apnoea (OSA), is collected worldwide. We asked whether the changes in CPAP adherence patterns of might constitute an alert for COVID-19.

METHODS

We analysed preliminary results of telemonitoring data, recorded between February 1 and April 30, 2020, on OSA patients followed by our sleep clinics and diagnosed with COVID-19.

RESULTS

CPAP telemonitoring data from the first 19 patients diagnosed with COVID-19 showed a clear decrease or halt in adherence in the 20 days immediately preceding COVID-19 diagnosis compared to an earlier period (p < 0.01).

CONCLUSION

Patterns of continuous positive airway pressure device use by obstructive sleep apnoea patients collected through telemonitoring can indicate the onset of COVID-19 symptoms. Existing telemonitoring platforms could be immediately used to screen for COVID-19, and for other respiratory infections, in this large at-risk population.

摘要

目的

尽早发现新冠肺炎患者对于遏制感染传播至关重要。现有的数字工具已得到扩展以解决这一问题。每晚都会收集全球范围内关于持续气道正压通气(CPAP)设备使用情况的远程监测数据,CPAP是阻塞性睡眠呼吸暂停(OSA)的一线治疗方法。我们研究了CPAP依从模式的变化是否可能构成新冠肺炎的警报。

方法

我们分析了2020年2月1日至4月30日期间,由我们的睡眠诊所随访并被诊断为新冠肺炎的OSA患者的远程监测数据的初步结果。

结果

前19例被诊断为新冠肺炎患者的CPAP远程监测数据显示,与早期相比,在新冠肺炎诊断前20天内,依从性明显下降或停止(p < 0.01)。

结论

通过远程监测收集的阻塞性睡眠呼吸暂停患者持续气道正压通气设备的使用模式可表明新冠肺炎症状的出现。现有的远程监测平台可立即用于在这一庞大的高危人群中筛查新冠肺炎及其他呼吸道感染。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01a7/8842445/7e4015e349fd/10.1177_20552076211002957-fig1.jpg

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