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无基础疾病的双侧卵巢静脉血栓形成:一例报告

Bilateral ovarian vein thrombosis without underlying conditions: A case report.

作者信息

Takazawa Ippei, Matsubara Daisuke, Takahashi Yoshifumi, Matsubara Shigeki

机构信息

Department of Cardiovascular Surgery, Jichi Medical University, Shimotsuke, Tochigi, Japan.

Department of Vascular Surgery, Koga Red Cross Hospital, Koga, Ibaraki, Japan.

出版信息

J Obstet Gynaecol Res. 2022 Apr;48(4):1046-1049. doi: 10.1111/jog.15182. Epub 2022 Feb 17.

DOI:10.1111/jog.15182
PMID:35174580
Abstract

Ovarian vein thrombosis (OVT) usually occurs on the right side in women with underlying conditions such as pelvic diseases and thrombophilia or during the postpartum period. Here, we present a patient with bilateral OVTs without underlying conditions. A 63-year-old woman without remarkable past or family histories complained of mild lower abdominal pain. Computed tomography revealed bilateral OVTs, with the right-sided thrombus nearly progressing into the inferior vena cava. The presence of symptoms and risk of thrombus extension/pulmonary embolism (PE) led us to administer an oral anticoagulant (rivaroxaban) promptly. Her symptom improved gradually and bilateral OVTs disappeared by 3 months without any evidence of PE. The present case suggests that OVT can occur in a woman without underlying conditions, and the use of an anticoagulant may be a treatment option in such a case.

摘要

卵巢静脉血栓形成(OVT)通常发生在患有盆腔疾病和血栓形成倾向等基础疾病的女性右侧,或产后期间。在此,我们报告一例无基础疾病的双侧OVT患者。一名63岁女性,既往史和家族史均无显著异常,主诉轻度下腹痛。计算机断层扫描显示双侧OVT,右侧血栓几乎延伸至下腔静脉。鉴于症状的存在以及血栓延伸/肺栓塞(PE)的风险,我们立即给予口服抗凝剂(利伐沙班)。她的症状逐渐改善,3个月时双侧OVT消失,且无任何PE迹象。本病例表明,OVT可发生在无基础疾病的女性中,在这种情况下使用抗凝剂可能是一种治疗选择。

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引用本文的文献

1
Direct Oral Anticoagulants for the Treatment of Unusual-Site Venous Thrombosis: An Update.直接口服抗凝剂治疗罕见部位静脉血栓形成:最新进展
Pharmaceutics. 2025 Mar 7;17(3):342. doi: 10.3390/pharmaceutics17030342.
2
Choosing safe and effective anticoagulation to treat idiopathic ovarian vein thrombosis: using first principles of deep vein thrombosis management to treat a rare diagnosis: a case report and review of the literature.选择安全有效的抗凝治疗特发性卵巢静脉血栓形成:运用深静脉血栓形成管理的基本原则治疗罕见诊断:病例报告及文献复习。
J Med Case Rep. 2023 Apr 21;17(1):147. doi: 10.1186/s13256-023-03876-3.
3
Potential critical risks of pulmonary thromboembolism from an asymptomatic postpartum ovarian vein thrombosis: a case report.
无症状性产后卵巢静脉血栓形成致肺血栓栓塞症的潜在危急风险:病例报告。
BMC Pregnancy Childbirth. 2022 Apr 15;22(1):323. doi: 10.1186/s12884-022-04627-w.