Oman Medical Speciality Board, Muscat, Oman.
Department of Spine Surgery, Bharati Vidyapeeth Medical College Hospital, Pune, India.
Osteoporos Int. 2022 Jul;33(7):1493-1499. doi: 10.1007/s00198-022-06316-y. Epub 2022 Feb 17.
The study was conducted to establish the association of Schmorl's nodes and osteoporosis in a Middle Eastern cohort. The prevalence of SN in this sample was 41.1%. It was most frequent in the lumbar spine typically solitary central lesions. Over 88% Schmorl's node cases were osteoporotic/osteopenic and only 11.6% normal.
This study aims to identify the prevalence of Schmorl's nodes (SNs) in a cohort of Omani nationals, and also to determine any relation between osteoporosis and Schmorl's nodes.
This retrospective observational study was conducted on Omani nationals. One thousand three hundred and forty-eight DEXA scan patients were included. Of these, 545 patients had complete X-rays and MRI scans that would help determine the SN status. The X-rays and sagittal, coronal, and axial T2-weighted MR images were used to identify the presence and exact location of the Schmorl nodes by one orthopedic trainee and confirmed by the senior author. The correlation of each parameter with the presence of SN was analyzed by the independent-samples T test and one-way ANOVA.
The overall prevalence of SN in this population sample appeared to be 41.1%. Over 88% of the SN-positive cases were either osteopenic or frankly osteoporotic by the WHO definition. Vast majority of SNs (87.1%) occurred in the lumbar spine and were central in location and mostly solitary. Statistical analysis of the data revealed significant correlation between osteopenia or osteoporosis and the presence of SNs.
The prevalence of SN in the sample of Omanis studied was 41.1% and was most frequently seen in older men in the lumbar spine. It is strongly associated with osteoporosis/osteopenia (88.4%) and frequently presents as solitary central lesions.
本研究旨在确定中东海湾地区人群中 Schmorl 结节（SN）的患病率，并确定骨质疏松症与 Schmorl 结节之间的关系。
这是一项对阿曼国民进行的回顾性观察性研究。共纳入了 1348 名 DEXA 扫描患者。其中，545 名患者有完整的 X 光和 MRI 扫描，这有助于确定 SN 状态。X 光片和矢状位、冠状位和轴位 T2 加权磁共振图像用于通过一名骨科受训者确定 SN 的存在和确切位置，并由资深作者确认。通过独立样本 t 检验和单因素方差分析对每个参数与 SN 存在的相关性进行分析。
总体而言，该人群样本中 SN 的总体患病率似乎为 41.1%。超过 88%的 SN 阳性病例根据世卫组织的定义为骨质疏松症或明显的骨质疏松症。绝大多数 SN（87.1%）发生在腰椎，位置为中央，且多为单发。数据分析显示，骨质疏松症或骨质疏松症与 SN 的存在之间存在显著相关性。
在研究的阿曼人群样本中，SN 的患病率为 41.1%，在腰椎中最常见于老年男性。它与骨质疏松症/骨量减少（88.4%）强烈相关，并且常表现为单发中央病变。
