Suppr超能文献

创伤后事件暴露与 COVID-19 一线医护人员自杀意念之间的关联可由梦魇介导。

Nightmares mediate the association between traumatic event exposure and suicidal ideation in frontline medical workers exposed to COVID-19.

机构信息

NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Peking University Sixth Hospital, Peking University Institute of Mental Health, 51 Huayuanbei Road, Beijing 100191, China.

Faculty of Medicine, Department of Psychiatry, Chinese University of Hong Kong, Sha Tin, Hong Kong SAR, China.

出版信息

J Affect Disord. 2022 May 1;304:12-19. doi: 10.1016/j.jad.2022.02.033. Epub 2022 Feb 15.

Abstract

BACKGROUND

Trauma experience increases the risk of suicidal ideation, but little is known about potentially psychological mechanisms underlying this relationship. This study aims to examine the relationship between coronavirus disease 2019 (COVID-19)-related traumatic event (CTE) exposure and suicidal ideation among hospital workers, and identify mediating roles of sleep disturbances in this relationship.

METHODS

Workers in seven designated hospitals in Wuhan, China, were invited to participate in an online survey from May 27, 2020, to July 31, 2020. Participants completed a self-report questionnaire to evaluate demographic characteristics, level of CTE exposures, nightmare frequency, insomnia severity, symptoms of depression and anxiety, and suicidal ideation. A series of correlation analyses were performed, and a mediation model was generated to examine correlations between CTE exposure, sleep disturbances, and suicidal ideation.

RESULTS

A total of 16,220 hospital workers were included in the final analysis, 13.3% of them reported suicidal ideation in the past month. CTE exposure was significantly associated with insomnia severity, nightmare frequency, and suicidal ideation. After controlling potential confounders, nightmares but not insomnia, depression, or anxiety were shown to be independent risk factors for suicidal ideation. Pathway analyses showed that the relationship between CTE exposure and suicidal ideation was fully mediated by nightmares (proportion mediated 66.4%) after adjusting for demographic characteristics and psychological confounders.

LIMITATIONS

Cross-sectional design precluded the investigation of causal relationships.

CONCLUSIONS

CTE exposure increases risk of hospital workers' suicidal ideation that is mediated by nightmares, suggesting nightmares intervention might be considered as a component when developing suicide prevention strategies.

摘要

背景

创伤经历会增加自杀意念的风险,但人们对这种关系背后潜在的心理机制知之甚少。本研究旨在探讨新型冠状病毒肺炎(COVID-19)相关创伤事件(CTE)暴露与医务人员自杀意念之间的关系,并确定睡眠障碍在此关系中的中介作用。

方法

2020 年 5 月 27 日至 7 月 31 日,邀请中国武汉 7 家指定医院的工作人员参加在线调查。参与者完成了一份自我报告问卷,以评估人口统计学特征、CTE 暴露水平、噩梦频率、失眠严重程度、抑郁和焦虑症状以及自杀意念。进行了一系列相关分析,并生成了一个中介模型,以检验 CTE 暴露、睡眠障碍和自杀意念之间的相关性。

结果

共有 16220 名医院工作人员纳入最终分析,其中 13.3%的人在过去一个月有自杀意念。CTE 暴露与失眠严重程度、噩梦频率和自杀意念显著相关。在控制潜在混杂因素后,噩梦而非失眠、抑郁或焦虑被证明是自杀意念的独立危险因素。路径分析显示,在调整人口统计学特征和心理混杂因素后,CTE 暴露与自杀意念之间的关系完全由噩梦介导(中介比例为 66.4%)。

局限性

横断面设计排除了因果关系的研究。

结论

CTE 暴露增加了医务人员自杀意念的风险,而噩梦则介导了这种风险,这表明噩梦干预可能被认为是制定自杀预防策略的一个组成部分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73c2/8843324/bf71206b4bbc/gr1_lrg.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验