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阿司匹林治疗脑缺血的对照试验:一份补遗

Controlled trial of aspirin in cerebral ischemia: an addendum.

作者信息

Lemak N A, Fields W S, Gary H E

出版信息

Neurology. 1986 May;36(5):705-10. doi: 10.1212/wnl.36.5.705.

Abstract

Patients (303) who had had carotid territory transient ischemic attacks were randomly assigned to aspirin or placebo treatments. Patients with amaurosis fugax responded as well to aspirin as those with hemisphere events. Patients with lesions of the appropriate carotid artery responded better to aspirin therapy than patients with no lesion or an occlusion. The aspirin effect was the same across all risk-factor groups. Smoking had no effect on clinical outcome.

摘要

303例有颈动脉供血区短暂性脑缺血发作的患者被随机分配接受阿司匹林或安慰剂治疗。一过性黑矇患者对阿司匹林的反应与半球事件患者相同。有相应颈动脉病变的患者对阿司匹林治疗的反应比无病变或有闭塞的患者更好。阿司匹林在所有风险因素组中的效果相同。吸烟对临床结果无影响。

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