European Centre for Disease Prevention and Control (ECDC), Solna, Sweden.
Republic of Estonia Health Board, Tallinn, Estonia.
Euro Surveill. 2022 Feb;27(7). doi: 10.2807/1560-7917.ES.2022.27.7.2200060.
Despite high COVID-19 vaccine coverage in the EU/EEA, there are increasing reports of SARS-CoV-2 infections and hospitalisations in vaccinated individuals. Using surveillance data from Estonia, Ireland, Luxembourg and Slovakia (January-November 2021), we estimated risk reduction of severe outcomes in vaccinated cases. Increasing age remains the most important driver of severity, and vaccination significantly reduces risk in all ages for hospitalisation (adjusted relative risk (aRR): 0.32; 95% confidence interval (CI): 0.26-0.39) and death (aRR: 0.20; 95% CI: 0.13-0.29).
尽管欧盟/欧洲经济区的 COVID-19 疫苗接种率很高,但越来越多的报告显示接种疫苗的个体中仍有 SARS-CoV-2 感染和住院病例。我们使用来自爱沙尼亚、爱尔兰、卢森堡和斯洛伐克的监测数据(2021 年 1 月至 11 月),估算了接种疫苗者发生严重后果的风险降低情况。年龄增长仍是严重程度的最重要驱动因素,而疫苗接种在各年龄段均显著降低了住院(校正相对风险[aRR]:0.32;95%置信区间[CI]:0.26-0.39)和死亡(aRR:0.20;95% CI:0.13-0.29)的风险。