Department of Neurology, the Ordos Central Hospital, Ordos City 017000, Inner Mongolia Province, China.
Department of Interventional Medicine, Yantai Mountain Hospital, Yantai City 264003, Shandong Province, China.
J Healthc Eng. 2022 Feb 8;2022:1357737. doi: 10.1155/2022/1357737. eCollection 2022.
To explore the correlation between selection of time window for acute cerebral infarction (ACI) and efficacy of intravascular stent implantation.
The clinical data of 84 ACI patients treated in our hospital from March 2019 to March 2020 were selected for the retrospective analysis, all study subjects received intravascular stent implantation, and after discharge, patients were assessed by the Modified Rankin Scale (mRS) and divided into the good prognosis group ( = 46, mRS score ≤2 points) and poor prognosis group ( = 38, mRS score >2 points). The clinical data of patients in the two groups at admission underwent univariate analysis, the indicators presenting < 0.05 were included in the logistic regression model, and the correlation between patients' treatment time window and clinical effect was analyzed by multivariate logistic regression analysis and linear fitting analysis.
According to the multivariate logistic regression analysis, low-density lipoprotein (LDL), time window, and blood glucose level before treatment were the independent factors affecting patients' treatment effect and were associated with the efficacy of intravascular stent implantation ( was 0.790, 0.889, and 0.672, respectively).
LDL, time window, and blood glucose level before treatment are the important factors affecting the efficacy of intravascular stent implantation for ACI patients, among which the time window is most significantly associated with the clinical effect. Therefore, ACI patients should accept clinical treatment as early as possible.
探讨急性脑梗死（ACI）时间窗选择与血管内支架植入疗效的相关性。
回顾性分析 2019 年 3 月至 2020 年 3 月我院收治的 84 例 ACI 患者的临床资料，所有研究对象均接受血管内支架植入治疗，出院后采用改良 Rankin 量表（mRS）对患者进行评估，分为预后良好组（ = 46，mRS 评分≤2 分）和预后不良组（ = 38，mRS 评分>2 分）。对两组患者入院时的临床资料进行单因素分析，将差异有统计学意义的指标纳入 Logistic 回归模型，采用多元 Logistic 回归分析和线性拟合分析患者的治疗时间窗与临床疗效的相关性。
根据多元 Logistic 回归分析，低密度脂蛋白（LDL）、治疗时间窗和治疗前血糖水平是影响患者治疗效果的独立因素，与血管内支架植入的疗效相关（分别为 = 0.790、0.889 和 0.672）。
LDL、治疗时间窗和治疗前血糖水平是影响 ACI 患者血管内支架植入疗效的重要因素，其中时间窗与临床疗效的相关性最为显著。因此，ACI 患者应尽早接受临床治疗。
