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[电离辐射对犬骨髓分离细胞血红蛋白功能特性的影响]

[The effect of ionizing radiation on the functional properties of hemoglobin from fractionated cells of dog bone marrow].

作者信息

Sukhomlinov B F, Sibirnaia N A

出版信息

Radiobiologiia. 1986 Mar-Apr;26(2):257-61.

PMID:3517945
Abstract

Cell populations of dog bone marrow enriched by erythroid cells were obtained by fractionation in a sucrose density gradient. Functional properties of the haemoglobin isolated from nucleate erythrocyte precursors were studied during the radiation injury development. The haemoglobin of later nucleate forms of the erythroid series of irradiated dog bone marrow exhibited an increase in its affinity to oxygen.

摘要

通过在蔗糖密度梯度中进行分级分离,获得了富含红细胞的犬骨髓细胞群体。在辐射损伤发展过程中,研究了从有核红细胞前体中分离出的血红蛋白的功能特性。受辐照犬骨髓红细胞系列中较晚期有核形式的血红蛋白对氧的亲和力增加。

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