Institute of Global Health, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Institute of Global Health, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Lancet Glob Health. 2022 Mar;10(3):e409-e415. doi: 10.1016/S2214-109X(21)00549-0.
Snakebite envenoming has a substantial health and socioeconomic effect in rural communities. However, there are insufficient epidemiological and animal data, which prevents accurate assessment on the effects of snakebite. We aimed to assess the health and socioeconomic effect of snakebite using a One Health perspective.
In this cross-sectional survey-based study, we assessed the health and socioeconomic effects of snakebite data using a multicluster survey that was previously done as part of the SNAKE-BYTE project in the Terai region, Nepal. Health effect was measured in terms of disability-adjusted life years (DALYs). Livelihood losses encompassed out-of-pocket health-care expenditures, losses of productivity due to days off work, and the losses due to mortality and treatment costs in domestic animals. Mortality losses in domestic animals were also estimated as animal loss equivalents, and overall human and animal health effect expressed using modified DALYs for zoonotic disease (zDALYs).
We estimate an annual snakebite burden of 200 799 DALYs (95% CI 103 137-357 805), mostly due to mortality in children and women. Snakebite is estimated to lead to US$2·8 million in yearly livelihood losses associated with human and animal cases. Overall, we estimate a yearly human and animal health burden of 202 595 zDALYs (104 300-360 284).
These findings present robust evidence on the extent of snakebite's health and socioeconomic effect and emphasise the need for a One Health perspective. The results also stress how improved data collection at the community level is crucial for improved assessments of its effect.
Swiss National Science Foundation.
蛇伤在农村社区具有重大的健康和社会经济影响。然而，由于缺乏流行病学和动物数据，无法准确评估蛇伤的影响。我们旨在从“同一健康”的角度评估蛇伤的健康和社会经济影响。
在这项基于横断面调查的研究中，我们使用多集群调查评估了蛇伤数据的健康和社会经济影响，该调查是作为尼泊尔特莱地区 SNAKE-BYTE 项目的一部分进行的。健康影响以伤残调整生命年（DALY）衡量。生计损失包括医疗保健自付费用、因旷工而导致的生产力损失以及家畜因死亡和治疗费用造成的损失。还估算了家畜死亡造成的动物损失当量，并使用人畜共患疾病的修正 DALY（zDALY）来表示人和动物的总体健康影响。
我们估计每年有 200799 个 DALY（95%CI 103137-357805）的蛇伤负担，主要是儿童和妇女的死亡率造成的。每年与人类和动物病例相关的生计损失估计为 280 万美元。总体而言，我们估计每年有 202595 个人畜共患疾病的 zDALY（104300-360284）的健康负担。
这些发现提供了关于蛇伤健康和社会经济影响程度的可靠证据，并强调了“同一健康”观点的必要性。结果还强调了在社区层面改进数据收集对于改进其影响评估的重要性。
瑞士国家科学基金会。
