Maisner Rose S, Song Amy, Zhou Benjamin, Srinivasan Nivetha, Thepmankorn Parisorn, Siniakowicz Claudia, Ayyala Haripriya S
From the Division of Plastic and Reconstructive Surgery, Rutgers-New Jersey Medical School, Newark, NJ.
Division of Plastic and Reconstructive Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.
Ann Plast Surg. 2022 May 1;88(3 Suppl 3):S266-S273. doi: 10.1097/SAP.0000000000003077.
Since 1999, nearly 841,000 individuals have died from overdoses, 29% involving prescription opioids. Use of opioids for postoperative pain lacks evidence-based guidelines, and despite studies showing the efficacy of nonopioid agents in reducing postoperative morbidity, opioids are still routinely prescribed. However, multiple states are adopting prescription drug monitoring programs and prescription drug laws. The authors sought to investigate recent opioid prescription patterns among plastic surgeons.
This cross-sectional study used "Medicare Provider Utilization and Payment Data: Part D Prescriber" provided by the Centers for Medicare & Medicaid Services from 2016 to 2018. Entries were filtered to include plastic surgeons. Demographic variables included surgeon sex, geographic region and state, board certification status, and length of experience. The surgeon's practice was designated as academic, private, or both. Outcomes included total opioid claims, opioid prescriber rate, and days per claim. Kruskal-Wallis tests were used for statistical comparison (α = .05).
From 2016 to 2018, plastic surgeons wrote 289,525 opioid prescriptions for 1,729,523 days (6.0 days per prescription), totaling $3,346,979.39. In 2018, 62.2% of plastic surgeons prescribed 0 to 10 opioids, 36.5% prescribed 11 to 50 opioids, and 1.3% prescribed more than 50. Furthermore, 99.5% of plastic surgeons prescribing opioids are practicing in metropolitan areas (rural-urban commuting area codes 1-3). Plastic surgeons who were male or were board certified had significantly lower opioid prescriber rates (P < 0.001). There were no significant variations in outcomes by length of surgeon experience. Geographic region was significantly associated with opioid prescription rates and days per claim, with Southern plastic surgeons having lower rates (P < 0.001) and those Northeastern ones prescribing shorter courses (P = 0.004). The number of opioid claims, days per claim, and opioid prescriber rates were all significantly lower in 2018 than in 2017 and 2016 (P < 0.001).
Prescriptions written by plastic surgeons may have contributed to the opioid epidemic, but 2018 data suggest opioids are becoming less routine in postoperative pain control. Further studies are warranted to assess factors related to reduced and shorter opioid prescriptions by plastic surgeons in the South and Northeast, respectively. Such insight, if adopted into law and implemented into clinical practice, may help reduce the burden of the opioid epidemic.
自1999年以来,近84.1万人死于药物过量,其中29%涉及处方阿片类药物。使用阿片类药物控制术后疼痛缺乏循证指南,尽管有研究表明非阿片类药物在降低术后发病率方面的疗效,但阿片类药物仍被常规处方。然而,多个州正在采用处方药监测计划和处方药法律。作者试图调查整形外科医生近期的阿片类药物处方模式。
这项横断面研究使用了医疗保险和医疗补助服务中心提供的2016年至2018年的“医疗保险提供者利用和支付数据:D部分开处方者”。筛选条目以纳入整形外科医生。人口统计学变量包括外科医生的性别、地理区域和州、委员会认证状态以及从业年限。外科医生的执业类型被指定为学术型、私人型或两者兼有。结果包括阿片类药物总索赔量、阿片类药物开处方率以及每次索赔的天数。使用Kruskal-Wallis检验进行统计比较(α = 0.05)。
2016年至2018年,整形外科医生开出了289,525张阿片类药物处方,共计1,729,523天(每张处方6.0天),总计3,346,979.39美元。2018年,62.2%的整形外科医生开出0至10张阿片类药物处方,36.5%开出11至50张,1.3%开出超过50张。此外,99.5%开阿片类药物处方的整形外科医生在大都市地区执业(城乡通勤区号为1 - 3)。男性或获得委员会认证的整形外科医生的阿片类药物开处方率显著较低(P < 0.001)。外科医生的从业年限对结果没有显著差异。地理区域与阿片类药物处方率和每次索赔天数显著相关,南部的整形外科医生处方率较低(P < 0.001),而东北部的医生开的疗程较短(P = 0.004)。2018年的阿片类药物索赔量、每次索赔天数和阿片类药物开处方率均显著低于2017年和2016年(P < 0.001)。
整形外科医生开具的处方可能助长了阿片类药物流行,但2018年的数据表明,阿片类药物在术后疼痛控制中使用得越来越不常规。有必要进一步研究评估分别与南部和东北部整形外科医生减少和缩短阿片类药物处方相关的因素。这种见解如果被纳入法律并应用于临床实践,可能有助于减轻阿片类药物流行的负担。