Manzoor Sabeena, Wani Shoib Mohmad, Ahmad Mir Sajad, Rizwan Danish
Department of Food Technology, Jamia Hamdard University, Delhi, India.
Department of Food Science & Technology, University of Kashmir Hazratbal Srinagar, Jammu and Kashmir, India; Department of Biotechnology, University of Kashmir Hazratbal Srinagar, Jammu and Kashmir, India.
Nutrition. 2022 Apr;96:111602. doi: 10.1016/j.nut.2022.111602. Epub 2022 Jan 19.
Probiotics and their food sources, prebiotics, are known to have qualities that help with gastrointestinal issues along with overall improvement in health and well-being. Pro- and prebiotics play a key role in neuroimmune processes. Their beneficial effects on health are linked to interactions of the gastrointestinal tract, immune system, and neurologic systems. The interaction between the microflora-gut-brain axis has a profound effect on brain function, thereby influencing the overall well-being of an individual. Nutritionists, researchers, regulatory bodies (World Health Organization/Food and Agriculture Organization), pharmaceutical, and food manufacturers are currently engaged in enhancing the potential of nutrition in health maintenance and disease prevention. Nutrition has the potential to increase psychological well-being and could be used much as are psychiatric drugs. Probiotics and prebiotics have evolved as promising therapeutic techniques to treat several disease conditions associated with the gastrointestinal tract. The aim of this review was to provide useful information about the use of probiotics and prebiotics in mitigation of various diseases such as COVID-19, congenital heart disease, diarrhea, inflammatory bowel disease, hypertension, genitourinary tract infection, colon cancer, immune system defense, mineral absorption, allergic disorders, and atopic dermatitis.
益生菌及其食物来源益生元，已知具有有助于解决胃肠道问题以及全面改善健康和幸福感的特性。益生菌和益生元在神经免疫过程中发挥关键作用。它们对健康的有益影响与胃肠道、免疫系统和神经系统的相互作用有关。微生物群-肠道-脑轴之间的相互作用对脑功能有深远影响，从而影响个体的整体幸福感。营养学家、研究人员、监管机构（世界卫生组织/联合国粮食及农业组织）、制药公司和食品制造商目前都在致力于提高营养在维持健康和预防疾病方面的潜力。营养有潜力增强心理健康，并且可以像精神药物一样被广泛使用。益生菌和益生元已发展成为治疗多种与胃肠道相关疾病的有前景的治疗技术。本综述的目的是提供有关益生菌和益生元在缓解各种疾病（如COVID-19、先天性心脏病、腹泻、炎症性肠病、高血压、泌尿生殖道感染、结肠癌、免疫系统防御、矿物质吸收、过敏性疾病和特应性皮炎）方面应用的有用信息。
