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Targeting omicron and other reported SARS-CoV-2 lineages by potent inhibitors of main protease 3CL Mpro: Molecular simulation analysis.

作者信息

Saeed Aamir, Ahmad Basharat, Majaz Sidra, Nouroz Faisal, Ahmad Ashfaq, Xie Yingqiu

机构信息

Department of Bioinformatics, Hazara University, Mansehra 21300, Pakistan.

Department of Bioinformatics, Hazara University, Mansehra 21300, Pakistan.

出版信息

J Infect. 2022 Jun;84(6):e133-e136. doi: 10.1016/j.jinf.2022.02.012. Epub 2022 Feb 17.

DOI:10.1016/j.jinf.2022.02.012
PMID:35183608
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8851874/
Abstract
摘要

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Travel Med Infect Dis. 2022 Jan-Feb;45:102242. doi: 10.1016/j.tmaid.2021.102242. Epub 2021 Dec 17.
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SARS-CoV-2 Nsp5 Activates NF-κB Pathway by Upregulating SUMOylation of MAVS.SARS-CoV-2 Nsp5 通过上调 MAVS 的 SUMOylation 激活 NF-κB 通路。
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Structural and Biochemical Analysis of the Dual Inhibition of MG-132 against SARS-CoV-2 Main Protease (Mpro/3CLpro) and Human Cathepsin-L.
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