Department of Surgery, Division of Transplantation, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Department of Medicine, Division of Nephrology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Clin Transplant. 2022 May;36(5):e14621. doi: 10.1111/ctr.14621. Epub 2022 Feb 27.
Despite regulations mandating follow-up laboratory testing for living kidney donors, less than half of transplant centers are in compliance. We sought to understand barriers to follow-up testing from the donors' perspective.
We surveyed our center's living kidney donors. Binary logistic regression was used to assess factors associated with follow-up testing completion.
Of 185 living kidney donors, 110 (59.4%) participated. Among them, 82 (74.5%) completed 6-month laboratory testing, 76 (69.1%) completed 12-month testing, 68 (61.8%) completed both, and 21 (19.0%) completed neither. Six-month testing completion was strongly associated with 12-month testing completion (OR 9.74, 95%CI: 2.23-42.50; p = .002). Those who disagreed with the statements, "Getting labs checked wasn't a priority for me," (OR for completing 6-month testing: 15.05, 95%CI: 3.70-61.18; p < .001; OR for completing 12-month testing: 5.85, 95%CI: 1.94-17.63; p = .002); and, "I forgot to get labs drawn [until I was reminded]" (OR for completing 6-month testing: 6.93, 95%CI: 1.59-30.08; p = .01; OR for completing 12-month testing: 6.55, 95%CI: 1.98-21.63; p = .002) were more likely to complete testing.
To our knowledge, this is the only study providing perspective on donor insights regarding the need for follow-up testing post donation. Interventions to influence living donor attitudes toward follow-up testing may improve follow-up.
尽管法规要求对活体肾脏捐献者进行后续实验室检测,但仍有不到一半的移植中心符合要求。我们试图从捐献者的角度了解阻碍后续检测的因素。
我们调查了本中心的活体肾脏捐献者。采用二项逻辑回归分析评估与完成后续检测相关的因素。
在 185 名活体肾脏捐献者中,有 110 名(59.4%)参与了调查。其中,82 名(74.5%)完成了 6 个月的实验室检测,76 名(69.1%)完成了 12 个月的检测,68 名(61.8%)同时完成了这两项检测,21 名(19.0%)两项都未完成。6 个月的检测完成情况与 12 个月的检测完成情况密切相关(OR 9.74,95%CI:2.23-42.50;p=0.002)。那些不同意“检测对我来说不是优先事项”的人(完成 6 个月检测的 OR:15.05,95%CI:3.70-61.18;p<0.001;完成 12 个月检测的 OR:5.85,95%CI:1.94-17.63;p=0.002);以及“我忘了去做检测,直到有人提醒我”(完成 6 个月检测的 OR:6.93,95%CI:1.59-30.08;p=0.01;完成 12 个月检测的 OR:6.55,95%CI:1.98-21.63;p=0.002)的人更有可能完成检测。
据我们所知,这是唯一一项从捐献者角度探讨对捐赠后后续检测需求的研究。干预措施可能会影响活体供者对后续检测的态度,从而改善后续检测的情况。