Pan L, Wu M, Wen Q R, Lyu J, Guo Y, Pei P, Du H D, Chen J S, Yu C Q, Chen L M, Li Liming
Department of Epidemiology and Biostatistics, School of Public Health, Peking University/Peking University Center for Public Health and Epidemic Preparedness and Response/Key Laboratory of Molecular Cardiovascular Sciences (Peking University), Ministry of Education,Beijing 100191, China.
Fuwai Hospital Chinese Academy of Medical Sciences, National Center for Cardiovascular Diseases, Beijing 100037, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2022 Feb 10;43(2):162-168. doi: 10.3760/cma.j.cn112338-20210402-00273.
To explore the relationship of physical activity and sedentary leisure time with muscle mass, strength, and quality in Chinese adults. Based on the second resurvey of China Kadoorie Biobank (CKB) in 2013-2014, logistic regression models were used to analyze the correlation of physical activity and sedentary leisure time with low muscle mass, grip strength, and muscle quality. A total of 24 245 participants were included in the analysis. The average daily physical activity level was (18.3±13.8) MET-h/d, and the sedentary leisure time was (4.4±1.9) hours. We took the lowest physical activity quartile as the reference and found that the participants' physical activity was negatively correlated to low muscle mass, strength, and quality. The s (95%s) of low appendicular skeletal muscle mass index (ASMI), low total skeletal muscle mass index (TSMI), low grip strength and low arm muscle quality (AMQ) were 0.68 (0.600.77), 0.66 (0.580.75), 0.82 (0.720.94) and 0.84 (0.740.95), respectively. The subtypes of physical activity, including those related to work, transportation, housework, and leisure, also showed negative correlations with low muscle mass, strength, and quality to varying degrees. Compared with participants with the shortest sedentary leisure time, those who had the longest were more likely to have low TSMI (=1.13, 95%: 0.99-1.30). Physical activity was negatively correlated with a lower risk of low muscle mass and strength, while longer sedentary leisure time positively correlated with low muscle mass.
探讨中国成年人身体活动和久坐休闲时间与肌肉量、力量及质量之间的关系。基于中国嘉道理生物银行（CKB）2013 - 2014年的第二次重复调查，采用逻辑回归模型分析身体活动和久坐休闲时间与低肌肉量、握力及肌肉质量的相关性。共有24245名参与者纳入分析。平均每日身体活动水平为（18.3±13.8）代谢当量小时/天，久坐休闲时间为（4.4±1.9）小时。我们将身体活动最低的四分位数作为参照，发现参与者的身体活动与低肌肉量、力量及质量呈负相关。低四肢骨骼肌质量指数（ASMI）、低总骨骼肌质量指数（TSMI）、低握力和低臂部肌肉质量（AMQ）的比值比（95%置信区间）分别为0.68（0.60 - 0.77）、0.66（0.58 - 0.75）、0.82（0.72 - 0.94）和0.84（0.74 - 0.95）。身体活动的亚型，包括与工作、交通、家务和休闲相关的活动，也在不同程度上与低肌肉量、力量及质量呈负相关。与久坐休闲时间最短的参与者相比，久坐休闲时间最长的参与者更易出现低TSMI（比值比 = 1.13，95%置信区间：0.99 - 1.30）。身体活动与低肌肉量和力量风险较低呈负相关，而较长的久坐休闲时间与低肌肉量呈正相关。
