Chandekar Kunal Ramesh, Sood Apurva, Kumar Rajender, Singh Harmandeep, Singh Shrawan Kumar
Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012 India.
Department of Urology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012 India.
Nucl Med Mol Imaging. 2022 Feb;56(1):63-66. doi: 10.1007/s13139-021-00729-z. Epub 2022 Jan 31.
Prostate-specific membrane antigen (PSMA) PET/CT is a well-acclaimed imaging modality for prostate cancer (PCa). However, many reports have highlighted PSMA radioligand uptake in a variety of benign tumors and lesions. We report a case of PCa in which Ga-PSMA-11 uptake was noted in the tracheal lumen. However, F-PSMA-1007 PET/CT was done on a subsequent day, which demonstrated no abnormal radiotracer uptake or morphological lesion within the tracheal lumen. This case highlights an uncommon finding of PSMA ligand uptake in a tracheal mucus plug (non-prostatic benign uptake), which may be misinterpreted as a false-positive finding.
前列腺特异性膜抗原（PSMA）PET/CT是一种广受赞誉的前列腺癌（PCa）成像方式。然而，许多报告都强调了PSMA放射性配体在多种良性肿瘤和病变中的摄取情况。我们报告了一例PCa病例，其中在气管腔内发现了镓-PSMA-11摄取。然而，随后一天进行了氟-PSMA-1007 PET/CT检查，结果显示气管腔内没有异常放射性示踪剂摄取或形态学病变。该病例突出了在气管黏液栓中出现PSMA配体摄取这一罕见发现（非前列腺良性摄取），这可能会被误解为假阳性结果。
