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睡眠模式能否预测自闭症谱系障碍儿童兄弟姐妹的自闭症特征?

Can sleep profiles predict autistic traits in siblings of children with autism spectrum disorder?

作者信息

Naeem Alshaimaa A, El-Boraie Hala A, Abou-Elsaad Tamer A, Khater Mohammed E, Manzar Md Dilshad, Spence David Warren, Pandi-Perumal Seithikurippu R, Zaki Nevin Fayez

机构信息

Egyptian ministry of health, Egypt.

Department of Psychiatry, Faculty of Medicine, Mansoura University, Egypt.

出版信息

Sleep Sci. 2021 Jul-Sep;14(3):214-223. doi: 10.5935/1984-0063.20200073.

Abstract

INTRODUCTION

As the prevalence of ASD (autism spectrum disorder) continues to rise, so does the need to evaluate the impact of associated difficulties on both the diagnosed child and the immediate family.

OBJECTIVES

The aim of the present study was to assess reports of sleep disturbance or abnormal sleep behaviours (sleep profiles) in the siblings of diagnosed autistic children (referred to throughout this study as high-risk siblings, or HR-sibs) and to determine if these sleep patterns correlated with evidence of disturbed sleep among their siblings who had full symptoms of autistic spectrum disorder.

MATERIAL AND METHODS

This case control cross-sectional study investigated 64 autistic children, 80 HR-sibs, and 80 typically developing children. Each study subject was assessed for sleep problems and autistic traits through the use of a sleep-wake diary, a school sleep habit survey, and a childhood autism spectrum test.

RESULTS

Children with autism spectrum disorders and their HR-sibs showed no significant differences regarding their sleep profiles. Typically, developing children had more middle insomnia than HR-sibs and had more wake latency.

CONCLUSION

Increased risks for sleep problems in children with autism and their HR-sibs emphasized the importance of early screening for sleep problems in children with autism and their siblings.

摘要

引言

随着自闭症谱系障碍(ASD)的患病率持续上升,评估相关困难对已确诊儿童及其直系亲属的影响的需求也在增加。

目的

本研究的目的是评估已确诊自闭症儿童的兄弟姐妹(在本研究中 throughout 称为高危兄弟姐妹,或HR-sibs)的睡眠障碍或异常睡眠行为(睡眠概况)报告,并确定这些睡眠模式是否与其患有自闭症谱系障碍全部症状的兄弟姐妹的睡眠障碍证据相关。

材料与方法

这项病例对照横断面研究调查了64名自闭症儿童、80名HR-sibs和80名发育正常的儿童。通过使用睡眠-觉醒日记、学校睡眠习惯调查和儿童自闭症谱系测试,对每个研究对象进行睡眠问题和自闭症特征评估。

结果

自闭症谱系障碍儿童及其HR-sibs在睡眠概况方面没有显著差异。通常,发育正常的儿童比HR-sibs有更多的中度失眠,且觉醒潜伏期更长。

结论

自闭症儿童及其HR-sibs睡眠问题风险增加,强调了对自闭症儿童及其兄弟姐妹进行睡眠问题早期筛查的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/baec/8848519/05192a931207/ssci-14-03-0214-g01.jpg

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