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静脉药物使用者的耻骨上骨髓炎:一例报告

Suprapubic Osteomyelitis in an Intravenous Drug User: A Case Report.

作者信息

Best Karimah, Hussien Siham, Malik Atika, Patel Salauni, Michael Miriam B

机构信息

Internal Medicine, American University of Antigua, Osbourn, ATG.

Internal Medicine, University of Maryland Midtown Campus, Baltimore, USA.

出版信息

Cureus. 2022 Jan 17;14(1):e21312. doi: 10.7759/cureus.21312. eCollection 2022 Jan.

DOI:10.7759/cureus.21312
PMID:35186571
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8848260/
Abstract

We discuss a case of methicillin-resistant (MRSA) osteomyelitis pubis in a 45-year-old female patient with an active history of intravenous (IV) drug injection. While IV drug users are typically infected with in cases of osteomyelitis of the pubic symphysis, our patient presented with a rare case of MRSA infection of the pubis symphysis. In this case, an investigation using magnetic resonance imaging (MRI), elevated levels of erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and culture was consistent with the diagnosis of osteomyelitis. Osteomyelitis pubis is an infection that causes necrosis and destruction of the pubic bone. This condition remains a rarity, as less than 1% of osteomyelitis cases are reported to involve the pubic symphysis, thus contributing to the delays observed between onset of symptoms and diagnosis. The goal of this case report is to promote awareness of this phenomenon to hasten diagnosis and early treatment. The recommended treatment is with IV antibiotics for MRSA coverage for four to six weeks' duration; however, our patient left against medical advice.

摘要

我们讨论了一例45岁有静脉注射毒品史的女性患者发生的耐甲氧西林金黄色葡萄球菌(MRSA)耻骨骨髓炎。虽然静脉注射毒品者在耻骨联合骨髓炎病例中通常感染的是[此处原文缺失相关病菌名称],但我们的患者呈现出一例罕见的耻骨联合MRSA感染病例。在该病例中,使用磁共振成像(MRI)进行的检查、红细胞沉降率(ESR)和C反应蛋白(CRP)水平升高以及培养结果均与骨髓炎的诊断相符。耻骨骨髓炎是一种导致耻骨骨质坏死和破坏的感染。这种情况仍然很罕见,因为据报道不到1%的骨髓炎病例累及耻骨联合,这导致了症状出现与诊断之间的延迟。本病例报告的目的是提高对这种现象的认识,以加快诊断和早期治疗。推荐的治疗方法是静脉注射覆盖MRSA的抗生素,持续四至六周;然而,我们的患者不听从医嘱擅自离开了。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e735/8848260/7a8f24948300/cureus-0014-00000021312-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e735/8848260/bd56cfbbb996/cureus-0014-00000021312-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e735/8848260/7a8f24948300/cureus-0014-00000021312-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e735/8848260/bd56cfbbb996/cureus-0014-00000021312-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e735/8848260/7a8f24948300/cureus-0014-00000021312-i02.jpg

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Septic arthritis and osteomyelitis of the symphysis pubis (osteitis pubis) from intravenous drug use.静脉注射吸毒所致耻骨联合的化脓性关节炎和骨髓炎(耻骨炎)
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