Kocamaz Murat, Aygit Ebru Demet, Inal Asli, Ocak Osman Bulut, Cicek Ugur, Gokyigit Birsen
Department of Ophthalmology, Darica Farabi Training and Research Hospital, Kocaeli, Turkey.
Department of Ophthalmology, University of Healty Sciences, Prof. Dr. N. Resat Belger Beyoglu Eye Training and Research Hospital, Istanbul, Turkey.
Beyoglu Eye J. 2019 Feb 20;4(1):28-31. doi: 10.14744/bej.2019.36854. eCollection 2019.
Duane retraction syndrome (DRS) is a congenital syndrome characterized by limitation in adduction and/or abduction eye movements and narrowing of the palpebral fissure in adduction, and may include globe retraction, upshoot or downshoot. Several systemic abnormalities, syndromes, and additional ocular findings can accompany DRS. This study is an evaluation of eye findings in patients with DRS.
The records of 632 patients with DRS who were followed up between 1995 and 2016 were reviewed retrospectively. Patients with a follow-up of less than 6 months and patients with a history of eye/cranial trauma or injury were not included in the study. Before the patients were examined, a detailed anamnesis was obtained. Details of the medical records, including additional systemic diseases, were recorded.
The average of follow-up time was 45 months (min-max: 6-128 months). There were 255 male and 377 female patients. A total of 34 patients (5.4%) had additional ocular abnormalities. The most frequently observed ocular pathologies associated with DRS were congenital ptosis (n=6, 0.94%) and coloboma of the iris (n=4, 0.63%).
Most cases of DRS are observed as isolated. However, various ocular and systemic abnormalities and syndromes are associated with DRS. In particular, synkinetic syndromes may frequently be seen alongside DRS. Therefore, a complete ocular examination and anamnesis are crucial in cases with DRS.
杜安眼球后退综合征（DRS）是一种先天性综合征，其特征为眼球内收和/或外展运动受限，内收时睑裂变窄，可能还包括眼球后退、上射或下射。DRS可能伴有多种全身异常、综合征及其他眼部表现。本研究旨在评估DRS患者的眼部表现。
回顾性分析1995年至2016年期间随访的632例DRS患者的病历。随访时间不足6个月的患者以及有眼/颅脑外伤史的患者未纳入本研究。在对患者进行检查前，详细询问了病史。记录了病历细节，包括其他全身性疾病。
平均随访时间为45个月（最短 - 最长：6 - 128个月）。男性患者255例，女性患者377例。共有34例患者（5.4%）伴有其他眼部异常。与DRS相关的最常见眼部病变为先天性上睑下垂（n = 6，0.94%）和虹膜缺损（n = 4，0.63%）。
大多数DRS病例为孤立性。然而，DRS与多种眼部和全身异常及综合征相关。特别是，联合运动综合征可能常与DRS同时出现。因此，对于DRS患者，全面的眼部检查和病史询问至关重要。
