Dev World Bioeth. 2023 Mar;23(1):34-40. doi: 10.1111/dewb.12346. Epub 2022 Feb 20.
The recent advances in assisted reproductive technology, such as hormonal stimulation, IVF, and intracytoplasmic sperm injection (ICSI), have made it possible to circumvent many causes of male and female factor infertility. However, uterine infertility is still considered an ''unconditionally infertile'' condition. Owing to the continued advances in organ transplantation, microvascular anastomosis techniques, and immunosuppressive medicine, the transplantation of organs is no longer restricted to the ones necessary for continued life. Quality-of-life enhancing types of transplantation, such as uterine transplantation, in recent years, have also entered the clinical arena. This undoubtedly brings new hope to such women, but also creates ethical challenges. Selection of the donor, the impact on the recipient and offspring, as well as challenges to moral and social norms are issues that cannot be ignored. In the present review, the ethical issues of transplantation of the uterus will be discussed in light of recent progress in the procedure.
近年来,辅助生殖技术如激素刺激、体外受精和胞浆内精子注射(ICSI)的进步,使得许多男性和女性因素引起的不孕得以解决。然而,子宫性不孕仍然被认为是“无条件不孕”的情况。由于器官移植、微血管吻合技术和免疫抑制药物的不断进步,器官移植不再局限于维持生命所必需的器官。近年来,提高生活质量的移植类型,如子宫移植,也已进入临床领域。这无疑给这些女性带来了新的希望,但也带来了伦理挑战。供体的选择、对受者和后代的影响,以及对道德和社会规范的挑战,都是不容忽视的问题。在本综述中,将根据该手术的最新进展,讨论子宫移植的伦理问题。