胶原蛋白如何变得“僵硬”。
How collagen becomes 'stiff'.
机构信息
Department of Medicine, University of Pennsylvania, Philadelphia, United States.
出版信息
Elife. 2022 Feb 21;11:e77041. doi: 10.7554/eLife.77041.
Abstract
Oxidative stress following a lung injury can alter the structure of collagen, causing it to stiffen and trigger the formation of a fibrotic scar that further hardens the tissue.
摘要
肺损伤后会产生氧化应激，改变胶原蛋白的结构，使其变硬，并引发纤维性瘢痕的形成，从而进一步使组织变硬。
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