Instem, Columbus, OH, USA.
Methods Mol Biol. 2022;2425:419-434. doi: 10.1007/978-1-0716-1960-5_16.
In silico toxicology protocols help ensure the results from computational toxicology models are performed and documented in a standardized, consistent, transparent, and accepted manner. In silico toxicology protocols for skin sensitization and genetic toxicology have been previously published and have been implemented within the Leadscope software. The following chapter outlines how such protocols have been deployed in the Leadscope platform including integration with toxicology databases and a battery of computational toxicology models.
计算机毒理学方案有助于确保计算毒理学模型的结果以标准化、一致、透明和可接受的方式进行和记录。皮肤致敏和遗传毒理学的计算机毒理学方案以前已经发表过，并已在 Leadscope 软件中实施。本章概述了这些方案如何在 Leadscope 平台中部署，包括与毒理学数据库和一系列计算毒理学模型的集成。
