Meyer B R, Bellucci A
Cardiol Clin. 1986 May;4(2):227-34.
A variety of anatomic abnormalities in the aging kidney have been identified, including decreased kidney size, increased glomerular sclerosis, and arteriolar vascular changes. Physiologic changes, including decreased renal blood flow, decreased glomerular filtration rate, altered renal tubular function, and altered renal endocrinologic function, have also been described. The clinical consequence of these changes is an altered ability of the aged kidney to respond to stress, either due to illness or due to therapeutic interventions by physicians. Extra caution and vigilance is therefore needed when caring for the elderly.
衰老肾脏中已发现多种解剖学异常，包括肾脏体积减小、肾小球硬化增加以及小动脉血管变化。生理变化也有描述，包括肾血流量减少、肾小球滤过率降低、肾小管功能改变以及肾脏内分泌功能改变。这些变化的临床后果是老年肾脏对应激（无论是由于疾病还是医生的治疗干预）的反应能力发生改变。因此，在照顾老年人时需要格外小心和警惕。
