Department of Dermatology, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Department of Dermatology, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Clin Dermatol. 2022 Jan-Feb;40(1):49-56. doi: 10.1016/j.clindermatol.2021.08.012. Epub 2021 Aug 8.
Stem cells have the ability to self-renew and differentiate into other cell types, which forms the foundation for their use in regenerative medicine and cosmetic dermatology. Adipose-derived stem cells have proven particularly attractive in aesthetics given their relative ease of collection and abundance. Stem cells have been employed for the treatment of androgenetic alopecia and skin rejuvenation with promising results, but their incorporation into cosmeceuticals is still in its infancy. Despite promising preclinical data and small clinical studies, additional randomized, controlled trials and standardization of treatment are needed to truly understand the place of stem cells in the aesthetics arena. We review the current literature and discuss current controversies and debates.
干细胞具有自我更新和分化为其他细胞类型的能力，这为它们在再生医学和美容皮肤科中的应用奠定了基础。脂肪来源的干细胞因其相对容易采集和丰富而在美容学中被证明特别有吸引力。干细胞已被用于治疗雄激素性脱发和皮肤年轻化，取得了有希望的结果，但它们在化妆品中的应用仍处于起步阶段。尽管有有前景的临床前数据和小型临床研究，但仍需要进行更多的随机对照试验和治疗标准化，以真正了解干细胞在美容领域的地位。我们回顾了当前的文献，并讨论了当前的争议和争论。
